2566715-93-1

2566715-93-1 structure

Name: KSK67
Chemical Name: KSK67
CAS Number: 2566715-93-1
Molecular Formula: C₂₂H₂₇N₃O₂
Molecular Weight: 365.47
Catalog: Signaling Pathways GPCR/G Protein Histamine Receptor
Create Date: 2023-09-30 18:39:12
Modify Date: 2024-01-13 16:16:10
KSK67 is a high-affinity dual sigma-2 and histamine H3 receptor antagonist, with Kis of 3.2, 1531, 101 nM for H3 receptor, sigma-1, sigma-2 receptor respectively. KSK67 can be used for research of nociceptive and neuropathic pain[1].

Name	KSK67

Description	KSK67 is a high-affinity dual sigma-2 and histamine H3 receptor antagonist, with Kis of 3.2, 1531, 101 nM for H3 receptor, sigma-1, sigma-2 receptor respectively. KSK67 can be used for research of nociceptive and neuropathic pain[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Sigma Receptor Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
Target	3.2, 1531, 101 nM (H3 receptor, sigma-1, sigma-2 receptor)[1]
References	[1]. Szczepańska K, et al. Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain. J Med Chem. 2023 Jul 27;66(14):9658-9683.

Molecular Formula	C₂₂H₂₇N₃O₂
Molecular Weight	365.47