787621-78-7
787621-78-7 structure
- Name: Estrogen receptor modulator 6
- Chemical Name: Estrogen receptor modulator 6
- CAS Number: 787621-78-7
- Molecular Formula: C18H16F2O3
- Molecular Weight: 318.32
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Estrogen receptor modulator 6 (compound 3a) is a highly specific and potent agonist of the estrogen receptor (ER) β with a remarkable affinity (K i = 0.44 nM). This compound exhibits an impressive 19-fold selectivity for ERβ over ERα, as evidenced by its affinity (K i = 8.4 nM).
| Name | Estrogen receptor modulator 6 |
|---|
| Description | Estrogen receptor modulator 6 (compound 3a) is a highly specific and potent agonist of the estrogen receptor (ER) β with a remarkable affinity (K i = 0.44 nM). This compound exhibits an impressive 19-fold selectivity for ERβ over ERα, as evidenced by its affinity (K i = 8.4 nM). |
|---|---|
| References | 1. Richardson TI, et al. Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 5: Combined A- and C-ring structure-activity relationship studies. Bioorg Med Chem Lett. 2007;17(20):5563-5566. |
| Molecular Formula | C18H16F2O3 |
|---|---|
| Molecular Weight | 318.32 |