931078-17-0
931078-17-0 structure
- Name: CPI-905
- Chemical Name: CPI-905
- CAS Number: 931078-17-0
- Molecular Formula: C18H20N2O5
- Molecular Weight: 344.36
- Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
- Create Date: 2023-12-22 04:45:40
- Modify Date: 2024-02-02 11:34:34
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CPI-905 is a potent and selective EZH2 inhibitor with IC50 value of 39.5 nM.
| Name | CPI-905 |
|---|
| Description | CPI-905 is a potent and selective EZH2 inhibitor with IC50 value of 39.5 nM. |
|---|---|
| References | 1. Bradley WD, Arora S, Busby J, Balasubramanian S, Gehling VS, Nasveschuk CG, Vaswani RG, Yuan CC, Hatton C, Zhao F, Williamson KE, Iyer P, Méndez J, Campbell R, Cantone N, Garapaty-Rao S, Audia JE, Cook AS, Dakin LA, Albrecht BK, Harmange JC, Daniels DL, Cummings RT, Bryant BM, Normant E, Trojer P. EZH2 inhibitor efficacy in non-Hodgkin's lymphoma does not require suppression of H3K27 monomethylation. Chem Biol. 2014 Nov 20;21(11):1463-75. doi: 10.1016/j.chembiol.2014.09.017. PubMed PMID: 25457180. |
| Molecular Formula | C18H20N2O5 |
|---|---|
| Molecular Weight | 344.36 |