2250025-95-5
2250025-95-5 structure
- Name: Liproxstatin-1 hydrochloride
- Chemical Name: Liproxstatin-1 hydrochloride
- CAS Number: 2250025-95-5
- Molecular Formula: C19H22Cl2N4
- Molecular Weight: 377.31
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Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].
| Name | Liproxstatin-1 hydrochloride |
|---|
| Description | Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1]. |
|---|---|
| In Vitro | Liproxstatin-1 shows antiferroptotic activity with an IC 50 of approximately 38 nM in mouse embryonic fibroblasts [2]. |
| In Vivo | Liproxstatin-1 (10 mg/kg, i.p.) suppresses ferroptosis in human cells, Gpx4 -/- kidney and in an ischaemia/reperfusion-induced tissue injury model [1]. |
| Molecular Formula | C19H22Cl2N4 |
|---|---|
| Molecular Weight | 377.31 |