2944452-34-8

2944452-34-8 structure

2944452-34-8 structure

Name: EGFR-IN-88
Chemical Name: EGFR-IN-88
CAS Number: 2944452-34-8
Molecular Formula: C₂₂H₁₈Cl₂N₄O₂S
Molecular Weight: 473.37
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2024-04-08 16:30:23
Modify Date: 2024-04-08 16:30:23
EGFR-IN-88 (Compound 4i) is an EGFR inhibitor (IC50: 87 nM). EGFR-IN-88 shows cytotoxicity against A549 cell with an IC50? of 3.902? μM. EGFR-IN-88 can induce cell apoptosis[1].

Name	EGFR-IN-88

Description	EGFR-IN-88 (Compound 4i) is an EGFR inhibitor (IC50: 87 nM). EGFR-IN-88 shows cytotoxicity against A549 cell with an IC50? of 3.902? μM. EGFR-IN-88 can induce cell apoptosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	87 nM (EGFR)[1]
References	[1]. Ali SH, et al. Design, synthesis, and molecular docking studies of novel quinoxaline derivatives as anticancer agents. Chem Biol Drug Des. 2023 Aug;102(2):303-315.

Molecular Formula	C₂₂H₁₈Cl₂N₄O₂S
Molecular Weight	473.37