2252446-26-5

2252446-26-5 structure

Name: LSD1-UM-109
Chemical Name: LSD1-UM-109
CAS Number: 2252446-26-5
Molecular Formula: C₂₉H₂₇FN₆
Molecular Weight: 478.56
Catalog: Signaling Pathways Epigenetics Histone Demethylase
Create Date: 2024-01-07 16:50:08
Modify Date: 2024-01-07 16:50:08
LSD1-UM-109 is a ighly potent and reversible LSD1 inhibitor with an IC50 of 3.1 nM. LSD1-UM-109 inhibits cell growth with IC50 values of 0.6 nM in the MV4;11 acute leukemia cell line and 1.1 nM in the H1417 small-cell lung cancer cell line[1].

Name	LSD1-UM-109

Description	LSD1-UM-109 is a ighly potent and reversible LSD1 inhibitor with an IC50 of 3.1 nM. LSD1-UM-109 inhibits cell growth with IC50 values of 0.6 nM in the MV4;11 acute leukemia cell line and 1.1 nM in the H1417 small-cell lung cancer cell line[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Demethylase
Target	LSD1:3.1 nM (IC50)
References	[1]. Canhui Zheng, et al. Discovery of Pyrrolo[2,3- c]pyridines as Potent and Reversible LSD1 Inhibitors. ACS Med Chem Lett. 2023 Sep 21;14(10):1389-1395.

Molecular Formula	C₂₉H₂₇FN₆
Molecular Weight	478.56