835655-37-3

835655-37-3 structure

Name: TCL1(10-24)
Chemical Name: TCL1(10-24)
CAS Number: 835655-37-3
Molecular Formula: C₈₈H₁₂₃N₂₃O₂₃
Molecular Weight: 1871.06
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2024-03-12 23:40:25
Modify Date: 2024-03-12 23:40:25
TCL1(10-24) is a encompassing the betaA strand of human TCL1. TCL1(10-24) is a Akt inhibitor. TCL1(10-24) interacts with the Akt PH domain prevented phosphoinositide binding and hence inhibits membrane translocation and activation of Akt. TCL1(10-24) inhibits cellular proliferation and anti-apoptosis. TCL1(10-24) has tumor growth in vivo[1].

Name	TCL1(10-24)

Description	TCL1(10-24) is a encompassing the betaA strand of human TCL1. TCL1(10-24) is a Akt inhibitor. TCL1(10-24) interacts with the Akt PH domain prevented phosphoinositide binding and hence inhibits membrane translocation and activation of Akt. TCL1(10-24) inhibits cellular proliferation and anti-apoptosis. TCL1(10-24) has tumor growth in vivo[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> Akt
References	[1]. Makoto Hiromura, et al. Inhibition of Akt kinase activity by a peptide spanning the betaA strand of the proto-oncogene TCL1. J Biol Chem. 2004 Dec 17;279(51):53407-18.

Molecular Formula	C₈₈H₁₂₃N₂₃O₂₃
Molecular Weight	1871.06