1015855-75-0

1015855-75-0 structure
1015855-75-0 structure

Name N-[1-[(6-chloropyridin-3-yl)methyl]-4,4,5,5-tetradeuterioimidazol-2-yl]nitramide
Synonyms 1H-Imidazol-4,5-d-2-amine, 1-[(6-chloro-3-pyridinyl)methyl]-4,5-dihydro-d-N-nitro-
Imidacloprid-d4
Imidazolidin-4,4,5,5-d4
1-[(6-Chloro-3-pyridinyl)methyl]-N-nitro(H)-4,5-dihydro-1H-imidazol-2-amine
Description Imidacloprid-d4 is the deuterium labeled Imidacloprid[1]. Imidacloprid is an effective and widely used neonicotinoid pesticide to control pests of cereals, vegetables, tea and cotton[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Kim J, et al. Imidacloprid, a neonicotinoid insecticide, induces insulin resistance. J Toxicol Sci. 2013;38(5):655-60.  

Density 1.6±0.1 g/cm3
Boiling Point 442.3±55.0 °C at 760 mmHg
Molecular Formula C9H6ClD4N5O2
Molecular Weight 259.686
Flash Point 221.3±31.5 °C
Exact Mass 259.077423
PSA 86.34000
LogP -0.43
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.706
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn
Risk Phrases 22
RIDADR NONH for all modes of transport