CAS No. 112668-45-8

Name	1-(4-aminoimidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
Synonyms	4-amino-1-(2-hydroxy-2-methylpropyl)-1H-imidazo[4,5-c]quinoline 2-Hydroxy Imiquimod R 842 1-(2,hydroxy-2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine 1-(4-amino-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol

Density	1.34g/cm3
Boiling Point	513.6ºC at 760 mmHg
Molecular Formula	C₁₄H₁₆N₄O
Molecular Weight	256.30300
Flash Point	264.4ºC
Exact Mass	256.13200
PSA	77.69000
LogP	1.86770
Vapour Pressure	2.26E-11mmHg at 25°C
Index of Refraction	1.685

129655-65-8

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Literature: Riker Laboratories, Inc. Patent: US4689338 A1, 1987 ; US 4689338 A

200198-35-2

95-50-1

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Literature: Minnesota Mining and Manufacturing Company Patent: US5741908 A1, 1998 ;

1375262-91-1

~86%

112668-45-8

Literature: Shi, Ce; Xiong, Zhengming; Chittepu, Padmaja; Aldrich, Courtney C.; Ohlfest, John R.; Ferguson, David M. ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 6 p. 501 - 504

133860-77-2

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112668-45-8

Literature: Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

15151-57-2

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112668-45-8

Literature: Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

132521-66-5

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112668-45-8

Literature: Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

133860-78-3

~%

112668-45-8

Literature: Gerster, John F.; Lindstrom, Kyle J.; Miller, Richard L.; Tomai, Mark A.; Birmachu, Woubalem; Bomersine, Shannon N.; Gibson, Shiela J.; Imbertson, Linda M.; Jacobson, Joel R.; Knafla, Roy T.; Maye, Peter V.; Nikolaides, Nickolas; Oneyemi, Folakemi Y.; Parkhurst, Gwen J.; Pecore, Sharon E.; Reiter, Michael J.; Scribner, Lisa S.; Testerman, Tracy L.; Thompson, Natalie J.; Wagner, Tammy L.; Weeks, Charles E.; Andre, Jean-Denis; Lagain, Daniel; Bastard, Yvon; Lupu, Michel Journal of Medicinal Chemistry, 2005 , vol. 48, # 10 p. 3481 - 3491

1375262-89-7

~%

112668-45-8

Literature: Shi, Ce; Xiong, Zhengming; Chittepu, Padmaja; Aldrich, Courtney C.; Ohlfest, John R.; Ferguson, David M. ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 6 p. 501 - 504

1158522-08-7	940364-43-2
134104-43-1	1251632-90-2
131615-57-1	6906-52-1
1208765-13-2	930439-75-1
1018584-77-4	1375289-11-4

Precursor 7
95-50-1 1375262-91-1 133860-77-2 15151-57-2
132521-66-5 133860-78-3 1375262-89-7
DownStream 0