29745-04-8

29745-04-8 structure

Name: (±)-Norcantharidin
Chemical Name: Norcantharidin
CAS Number: 29745-04-8
Molecular Formula: C₈H₈O₄
Molecular Weight: 168.147
Catalog: API Antineoplastic agents Natural source antineoplastic agents
Create Date: 2018-07-17 23:10:53
Modify Date: 2024-01-06 18:03:05
(±)-Norcantharidin ((±)-NCTD) is a compound possessing anti-angiogenetic activity with potential use in anti-cancertherapy. (±)-Norcantharidin could prevent tumorigenesis by inhibiting cell proliferation, inducing apoptosis and the cell cycle arrest, and anti-angiogenic effects[1].

Name	Norcantharidin
Synonyms	(1R,2S,6R,7S)-4,10-Dioxatricyclo[5.2.1.0]decane-3,5-dione norcantharadin (3aR,4S,7R,7aS)-hexahydro-4,7-epoxy-2-benzofuran-1,3-dione 4,10-dioxatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione exo-3,6-Epoxyhexahydrophthalic Anhydride exo-7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic Anhydride MFCD00213361 Isocantharidin demethyl cantharidin 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-, (4R,7S)- 7-oxabicyclo[2,2,1]heptane-2,3-dicarboxylc acid anhydride 7-oxabicyclo[2,2,1]heptane-2,3-dicarboxylic acid anhydride 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-, (3aR,4S,7R,7aS)- (1R,7S)-4,10-Dioxatricyclo[5.2.1.0]decane-3,5-dione endothallanhydride Norcantharidin exo,exo-4,10-dioxatricyclo[5.2.1.02.6]decane-3,5-dione Exo-7-oxabicyclo(2.2.1)h (4R,7S)-hexahydro-4,7-epoxy-2-benzofuran-1,3-dione

Description	(±)-Norcantharidin ((±)-NCTD) is a compound possessing anti-angiogenetic activity with potential use in anti-cancertherapy. (±)-Norcantharidin could prevent tumorigenesis by inhibiting cell proliferation, inducing apoptosis and the cell cycle arrest, and anti-angiogenic effects[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Inflammation/Immunology
In Vitro	(±)-Norcantharidin ((±)-NCTD) inhibits HMC cell proliferation, induces apoptosis, and affects the cell cycle[1].
References	[1]. Ye K, et al. Effect of norcantharidin on the proliferation, apoptosis, and cell cycle of human mesangialcells. Ren Fail. 2017 Nov;39(1):458-464.

CHEMICAL NAME :: 7-Oxabicyclo(2.2.1)heptane-2,3-dicarboxylic anhydride, exo-

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953- Volume(issue)/page/year: 35,823,1987

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Risk Phrases	R36/37/38
Safety Phrases	26-36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	RN8400000
HS Code	2932999099

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%