329216-67-3
329216-67-3 structure
- Name: 4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazineethanol
- Chemical Name: 2-(4-benzo[b][1,4]benzothiazepin-6-ylpiperazin-1-yl)ethanol
- CAS Number: 329216-67-3
- Molecular Formula: C19H21N3OS
- Molecular Weight: 339.454
- Create Date: 2018-03-22 08:00:00
- Modify Date: 2024-01-03 11:06:30
| Name | 2-(4-benzo[b][1,4]benzothiazepin-6-ylpiperazin-1-yl)ethanol |
|---|---|
| Synonyms |
1-Piperazineethanol, 4-dibenzo[b,f][1,4]thiazepin-11-yl-
Quetiapine Hydroxy Impurity Dihydrochloride Salt 2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl]ethanol 4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazineethanol T C676 BS INJ C- AT6N DNTJ D2Q O-Dealkyl Quetiapine 2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethanol Quetiapine Hydroxy Impurity 4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazineethanol Quetiapine Impurity 2 |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 523.4±60.0 °C at 760 mmHg |
| Molecular Formula | C19H21N3OS |
| Molecular Weight | 339.454 |
| Flash Point | 270.3±32.9 °C |
| Exact Mass | 339.140533 |
| PSA | 64.37000 |
| LogP | 2.27 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
| Index of Refraction | 1.683 |
| Storage condition | 2-8°C |
|
~51%
329216-67-3 |
| Literature: CONCERT PHARMACEUTICALS INC. Patent: WO2008/66620 A2, 2008 ; Location in patent: Page/Page column 23-24 ; |
|
~83%
329216-67-3 |
| Literature: AUSPEX PHARMACEUTICALS, INC. Patent: US2010/69356 A1, 2010 ; Location in patent: Page/Page column 26-27 ; US 20100069356 A1 |
|
~92%
329216-67-3
Detail
|
| Literature: UNION QUIMICO-FARMACEUTICA S.A. Patent: WO2006/94549 A1, 2006 ; Location in patent: Page/Page column 17-18 ; |
|
~%
329216-67-3 |
| Literature: Warawa; Migler; Ohnmacht; Needles; Gatos; McLaren; Nelson; Kirkland Journal of Medicinal Chemistry, 2001 , vol. 44, # 3 p. 372 - 389 |
