Henan Tianfu Chemical Co., Ltd.
China
Product Name: tropacocaine hydrochloride
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

637-23-0

637-23-0 structure

637-23-0 structure

Name: 8-Azabicyclo[3.2.1]octan-3-ol,8-methyl-, benzoate (ester), hydrochloride, (3-exo)- (9CI)
Chemical Name: tropacocaine hydrochloride
CAS Number: 637-23-0
Molecular Formula: C₁₅H₂₀ClNO₂
Molecular Weight: 281.77800
Create Date: 2018-12-29 19:23:00
Modify Date: 2024-01-02 12:03:55

Name	tropacocaine hydrochloride
Synonyms	Benzoesaeure-tropan-3exo-ylester,Hydrochlorid endo-benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester hydrochloride pseudotropine benzoate hydrochloride 3exo-benzoyloxy-tropane,hydrochloride 8-azabicyclo(3.2.1)octan-3-ol,8-methyl-,benzoate (ester),hydrochloride,ex benzoylpseudotropine hydrochloride Tropacaine hydrochloride Pseudotropin tropacocain hydrochloride 3exo-Benzoyloxy-tropan,Hydrochlorid Tropacocaine (8-methyl-8-azabicyclo[3.2.1]oct-3-yl) benzoate

Boiling Point	339.9ºC at 760 mmHg
Molecular Formula	C₁₅H₂₀ClNO₂
Molecular Weight	281.77800
Flash Point	122.3ºC
Exact Mass	281.11800
PSA	29.54000
LogP	3.20850

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YM4201000

CHEMICAL NAME :: 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, benzoate (ester), hydrochloride

CAS REGISTRY NUMBER :: 637-23-0

LAST UPDATED :: 198910

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C15-H19-N-O2.Cl-H

MOLECULAR WEIGHT :: 281.81

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 7,227,1934

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 465 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RCSADO Research Communications in Substances Abuse. (PJD Pub. Ltd., P.O.Box 966, Westbury, NY 11590) V.1- 1980- Volume(issue)/page/year: 5,279,1984

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 42 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic

REFERENCE :: WDMU** "Vergleichend-pharmakologische Untersuchungen ueber die haemolytische Wirkung und die Toxizitat der Lokalanaesthetika, Dissertation," Walther, M., Pharmakologischen Instit Martin Luther-Universitat Halle-Wittenburg, Ger. Dem. Rep., 1936 Volume(issue)/page/year: -,-,1936 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 120 mg/kg

SEX/DURATION :: female 7 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - Central Nervous System

REFERENCE :: RCSADO Research Communications in Substances Abuse. (PJD Pub. Ltd., P.O.Box 966, Westbury, NY 11590) V.1- 1980- Volume(issue)/page/year: 5,279,1984

HS Code	2933990090

98-88-4 structure

98-88-4

135-97-7 structure

135-97-7

~%

637-23-0 structure

637-23-0

Literature: WO2009/34042 A1, ; Page/Page column 10-11 ;

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%