Top Suppliers:I want be here


977-79-7

977-79-7 structure
977-79-7 structure
  • Name: Medrogestone
  • Chemical Name: Medrogestone
  • CAS Number: 977-79-7
  • Molecular Formula: C23H32O2
  • Molecular Weight: 340.49900
  • Create Date: 2018-09-25 10:36:12
  • Modify Date: 2024-01-02 19:02:46

Name Medrogestone
Synonyms EINECS 213-555-0
4,6-PREGNADIEN-6,17-DIMETHYL-3,20-DIONE
6,17-Dimethyl-4,6-pregnadien-3.20-dion
MFCD00271888
6,17-Dimethyl-pregnadien-(4,6)-dion-(3.20)
6,17-Dimethyl-pregna-4,6-dien-3.20-dion
6,17-dimethylpregna4,6-diene-3,20-dione
Density 1.08g/cm3
Boiling Point 467.2ºC at 760mmHg
Molecular Formula C23H32O2
Molecular Weight 340.49900
Flash Point 173.7ºC
Exact Mass 340.24000
PSA 34.14000
LogP 5.27970
Index of Refraction 1.549

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TU3832300
CHEMICAL NAME :
Pregna-4,6-diene-3,20-dione, 6,17-dimethyl-
CAS REGISTRY NUMBER :
977-79-7
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C23-H32-O2
MOLECULAR WEIGHT :
340.55

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
850 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4230702 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
20500 ug/kg
SEX/DURATION :
female 1 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
REFERENCE :
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 12,473,1966
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
300 mg/kg
SEX/DURATION :
female 15-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 12,473,1966
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
26250 ug/kg
SEX/DURATION :
female 21 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 12,473,1966
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
7500 ug/kg
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
REFERENCE :
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 12,473,1966