6637-10-1

6637-10-1 structure

Name: 2,3'-Bi-1H-indole,2,3-dihydro-
Chemical Name: 3-[(2R)-2,3-dihydro-1H-indol-2-yl]-1H-indole
CAS Number: 6637-10-1
Molecular Formula: C₁₆H₁₄N₂
Molecular Weight: 234.30
Catalog: Research Areas Cancer
Create Date: 2017-10-23 11:19:44
Modify Date: 2024-01-10 09:48:35
VPC13163 is a potent androgen receptor (AR) BF3 inhibitor with an IC50 of 0.31 µM. VPC13163 has anticancer effects[1].

Name	3-[(2R)-2,3-dihydro-1H-indol-2-yl]-1H-indole
Synonyms	2,3-dihydro-1H,1'H-[2,3']biindolyl 3-(indolin-2-yl)indole 2,3-dihydro-(1,4)dioxino(2,3-c)pyridin-7-carbaldehyde 2-(3-indolyl)-2,3-dihydroindole 2H,3H-[1,4]dioxino[2,3-c]pyridine-7-carbaldehyde 2,3-Dihydro-<2,3'-biindole> 3-(indolin-2-yl)-1H-indole 2-(3'-indolyl)indoline 2-(indol-3-yl)-2,3-dihydroindole 2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxaldehyde 2,3-dihydro[1,4]dioxino[2,3-c]pyridine-7-carbaldehyde

Description	VPC13163 is a potent androgen receptor (AR) BF3 inhibitor with an IC50 of 0.31 µM. VPC13163 has anticancer effects[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Androgen Receptor
Target	IC50: 0.31 µM (AR BF3)[1]
References	[1]. Ravi Shashi Nayana Munuganti, et al. Abstract 2508: The development of anti-androgens with a novel mechanism of action for treatment of castration-resistant prostate cancer. Cancer Res (2014) 74 (19_Supplement): 2508.