108853-09-4

108853-09-4 structure

Name: Chrysotobibenzyl
Chemical Name: 5-[2-(3,4-dimethoxyphenyl)ethyl]-1,2,3-trimethoxybenzene
CAS Number: 108853-09-4
Molecular Formula: C₁₉H₂₄O₅
Molecular Weight: 332.39
Catalog: Signaling Pathways Cytoskeleton Integrin
Create Date: 2017-03-07 08:02:09
Modify Date: 2024-01-11 12:16:35
Chrysotobibenzyl can be isolated from stem of Dendrobium pulchellum. Chrysotobibenzyl inhibits lung cancer cell (H460 and H292) migration, invasion, filopodia formation via Cav-1, integrins β1, β3, and αν, and EMT suppressions. Chrysotobibenzyl also sensitizes lung cancer cell death mediated by Cisplatin (HY-17394)[1].

Name	5-[2-(3,4-dimethoxyphenyl)ethyl]-1,2,3-trimethoxybenzene
Synonyms	Aloifol II dimethyl ether 3,3',4,4',5-pentamethoxybibenzyl 3,4,5,3',4'-pentamethoxybibenzyl Benzene,5-(2-(3,4-dimethoxyphenyl)ethyl)-1,2,3-trimethoxy gastrochilinin Chrysotobibenzyl

Description	Chrysotobibenzyl can be isolated from stem of Dendrobium pulchellum. Chrysotobibenzyl inhibits lung cancer cell (H460 and H292) migration, invasion, filopodia formation via Cav-1, integrins β1, β3, and αν, and EMT suppressions. Chrysotobibenzyl also sensitizes lung cancer cell death mediated by Cisplatin (HY-17394)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cytoskeleton >> Integrin
References	[1]. Petpiroon N, et al. Chrysotobibenzyl inhibition of lung cancer cell migration through Caveolin-1-dependent mediation of the integrin switch and the sensitization of lung cancer cells to cisplatin-mediated apoptosis. Phytomedicine. 2019 May;58:152888.