Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Benzenesulfonamide,4-methoxy-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Contact: Ms Wang

3567-08-6

3567-08-6 structure

3567-08-6 structure

Name: Benzenesulfonamide,4-methoxy-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-
Chemical Name: Glysobuzole
CAS Number: 3567-08-6
Molecular Formula: C₁₃H₁₇N₃O₃S₂
Molecular Weight: 327.42200
Create Date: 2018-06-23 07:14:40
Modify Date: 2024-01-12 20:38:05

Name	Glysobuzole
Synonyms	4-methoxy-benzenesulfonic acid-(5-isobutyl-[1,3,4]thiadiazol-2-ylamide) 5-<4-Methoxy-benzolsulfonylamino>-2-isobutyl-1,3,4-thiadiazol N-(5-isobutyl-[1,3,4]thiadiazol-2-yl)-4-methoxy-benzenesulfonamide 4-Methoxy-benzolsulfonsaeure-(5-isobutyl-[1,3,4]thiadiazol-2-ylamid) Isobuzole Wy-2340 Isopamin 5-<4-Methoxy-phenylsulfonylamino>-2-isobutyl-1,3,4-thiadiazol SADA

Density	1.37g/cm3
Boiling Point	517.5ºC at 760mmHg
Molecular Formula	C₁₃H₁₇N₃O₃S₂
Molecular Weight	327.42200
Flash Point	266.8ºC
Exact Mass	327.07100
PSA	117.80000
LogP	3.69980
Index of Refraction	1.589

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DB2780000

CHEMICAL NAME :: Benzenesulfonamide, N-(5-isobutyl-1,3,4-thiadiazol-2-yl)-p-methoxy-

CAS REGISTRY NUMBER :: 3567-08-6

BEILSTEIN REFERENCE NO. :: 0295174

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C13-H17-N3-O3-S2

MOLECULAR WEIGHT :: 327.45

WISWESSER LINE NOTATION :: T5NN DSJ CMSWR DO1& E1Y1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 534 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,13,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 468 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,13,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Behavioral - ataxia Endocrine - hypoglycemia Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 4,631,1962

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - muscle weakness Gastrointestinal - nausea or vomiting

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,13,1966 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 214 gm/kg/52W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,13,1966 *** REVIEWS *** TOXICOLOGY REVIEW ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1- 1950- Volume(issue)/page/year: 13,271,1970

HS Code	2935009090

503-74-2 structure

503-74-2

79-19-6 structure

79-19-6

98-68-0 structure

98-68-0

~%

3567-08-6 structure

3567-08-6

Literature: O'Neal,J.B. et al. Journal of Medicinal and Pharmaceutical Chemistry, 1962 , vol. 5, p. 617 - 626

Precursor 3
503-74-2 79-19-6 98-68-0
DownStream 0

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%