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1089280-53-4

1089280-53-4 structure
1089280-53-4 structure

Name tert-butyl 4-(4-amino-3-methoxyphenyl)piperidine-1-carboxylate
Synonyms 1,1-dimethylethyl 4-[4-amino-3-(methyloxy)phenyl]-1-piperidine carboxylate
1-Piperidinecarboxylic acid,4-(4-amino-3-methoxyphenyl)-,1,1-dimethylethyl ester
D-1291
Molecular Formula C17H26N2O3
Molecular Weight 306.40000
Exact Mass 306.19400
PSA 64.79000
LogP 3.91100

~10%

1089280-53-4 structure

1089280-53-4

Literature: SANOFI Patent: US2012/277220 A1, 2012 ; Location in patent: Page/Page column 17 ;

~80%

1089280-53-4 structure

1089280-53-4

Literature: Kuntz, Kevin; Uehling, David Edward; Waterson, Alex Gregory; Emmitte, Kyle Allen; Stevens, Kirk; Shotwell, John Brad; Smith, Stephon Cornell; Nailor, Kristen E.; Salovich, James M.; Wilson, Brian John; Cheung, Mui; Mook, Robert Anthony; Baum, Erich W.; Moorthy, Ganesh Patent: US2008/300242 A1, 2008 ; Location in patent: Page/Page column 109 ; US 20080300242 A1

~%

1089280-53-4 structure

1089280-53-4

Literature: ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; VASUDEVAN, Anil; PENNING, Thomas Dale; CHEN, Huanming; LIANG, Bo; WANG, Shaohui; WU, Fengchun; SHEN, Yan; LIU, Cuihua; ZOU, Zhenguang Patent: WO2012/97684 A1, 2012 ; Location in patent: Page/Page column 119-120 ; WO 2012/097684 A1

~%

1089280-53-4 structure

1089280-53-4

Literature: ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; VASUDEVAN, Anil; PENNING, Thomas Dale; CHEN, Huanming; LIANG, Bo; WANG, Shaohui; ZHAO, Zhongqiang; CHAI, Dikun; YANG, Leifu; GAO, Yingxiang Patent: WO2012/97682 A1, 2012 ;

~%

1089280-53-4 structure

1089280-53-4

Literature: ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; VASUDEVAN, Anil; PENNING, Thomas Dale; CHEN, Huanming; LIANG, Bo; WANG, Shaohui; ZHAO, Zhongqiang; CHAI, Dikun; YANG, Leifu; GAO, Yingxiang Patent: WO2012/97682 A1, 2012 ;

~%

1089280-53-4 structure

1089280-53-4

Literature: SANOFI Patent: US2012/277220 A1, 2012 ;

~%

1089280-53-4 structure

1089280-53-4

Literature: SANOFI Patent: US2012/277220 A1, 2012 ;

~%

1089280-53-4 structure

1089280-53-4

Literature: ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; VASUDEVAN, Anil; PENNING, Thomas Dale; CHEN, Huanming; LIANG, Bo; WANG, Shaohui; WU, Fengchun; SHEN, Yan; LIU, Cuihua; ZOU, Zhenguang Patent: WO2012/97684 A1, 2012 ; WO 2012/097684 A1

~%

1089280-53-4 structure

1089280-53-4

Literature: Mesaros, Eugen F.; Thieu, Tho V.; Wells, Gregory J.; Zificsak, Craig A.; Wagner, Jason C.; Breslin, Henry J.; Tripathy, Rabindranath; Diebold, James L.; McHugh, Robert J.; Wohler, Ashley T.; Quail, Matthew R.; Wan, Weihua; Lu, Lihui; Huang, Zeqi; Albom, Mark S.; Angeles, Thelma S.; Wells-Knecht, Kevin J.; Aimone, Lisa D.; Cheng, Mangeng; Ator, Mark A.; Ott, Gregory R.; Dorsey, Bruce D. Journal of Medicinal Chemistry, 2012 , vol. 55, # 1 p. 115 - 125