119738-57-7

119738-57-7 structure

Name: clerodendrin
Chemical Name: (2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-6-carboxy-4,5-dihydroxy-2-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
CAS Number: 119738-57-7
Molecular Formula: C₂₇H₂₆O₁₇
Molecular Weight: 622.48500
Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
Create Date: 2017-08-01 04:04:28
Modify Date: 2024-02-01 13:39:37
Clerodendrin is a nature product could be isolated from Lobelia chinensis. Clerodendrin is a potent dual Interleukin-4 (IL-4) inhibitor and β-hexosaminidase (Hex) inhibitor[1].

Name	(2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-6-carboxy-4,5-dihydroxy-2-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
Synonyms	Clerodendrin

Description	Clerodendrin is a nature product could be isolated from Lobelia chinensis. Clerodendrin is a potent dual Interleukin-4 (IL-4) inhibitor and β-hexosaminidase (Hex) inhibitor[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Inflammation/Immunology
In Vitro	Clerodendrin (10 μM; 1 and 3 h) inhibits IL-4 mRNA expression and the release of β-hexosaminidase in Propidium Iodide (HY-D0815)-induced RBL-2H3 cells[1].
References	[1]. Young KT, et, al. Inhibition of Interleukin-4 and β-Hexosaminidase Release in RBL-2H3 Cells by Compounds Isolated from Lobelia chinensis. 2021,27(4):251-6.