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  • DC Chemicals Limited
  • China
  • Product Name: S26948
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

353280-43-0

353280-43-0 structure
353280-43-0 structure
  • Name: S26948
  • Chemical Name: dimethyl 2-[[4-[2-(6-benzoyl-2-oxo-1,3-benzothiazol-3-yl)ethoxy]phenyl]methyl]propanedioate
  • CAS Number: 353280-43-0
  • Molecular Formula: C28H25NO7S
  • Molecular Weight: 519.56600
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
  • Create Date: 2016-06-20 04:13:59
  • Modify Date: 2024-01-27 18:29:55
  • S26948 is a specific peroxisome proliferator-activated receptor γ (PPARγ) modulator (EC50=8.83 nM) with potent antidiabetes and antiatherogenic effects. S26948 is a specific high-affinity agonist for PPARγ[1].

Name dimethyl 2-[[4-[2-(6-benzoyl-2-oxo-1,3-benzothiazol-3-yl)ethoxy]phenyl]methyl]propanedioate
Synonyms dimethyl 2-{4-[2-(6-benzoyl-2-oxo-1,3-benzothiazol-3(2H)-yl)ethoxy]benzyl}-malonate
Description S26948 is a specific peroxisome proliferator-activated receptor γ (PPARγ) modulator (EC50=8.83 nM) with potent antidiabetes and antiatherogenic effects. S26948 is a specific high-affinity agonist for PPARγ[1].
Related Catalog
References

[1]. Maria Carmen Carmona, et al. S 26948: a new specific peroxisome proliferator activated receptor gamma modulator with potent antidiabetes and antiatherogenic effects. Diabetes. 2007 Nov;56(11):2797-808.

Molecular Formula C28H25NO7S
Molecular Weight 519.56600
Exact Mass 519.13500
PSA 129.14000
LogP 3.87770
RIDADR NONH for all modes of transport

~83%

353280-43-0 structure

353280-43-0

Literature: Blanc-Delmas, Elodie; Lebegue, Nicolas; Wallez, Valerie; Leclerc, Veronique; Yous, Said; Carato, Pascal; Farce, Amaury; Bennejean, Caroline; Renard, Pierre; Caignard, Daniel-Henri; Audinot-Bouchez, Valerie; Chomarat, Pascale; Boutin, Jean; Hennuyer, Nathalie; Louche, Katie; Carmona, Maria Carmen; Staels, Bart; Penicaud, Luc; Casteilla, Louis; Lonchampt, Michel; Dacquet, Catherine; Chavatte, Philippe; Berthelot, Pascal; Lesieur, Daniel Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 22 p. 7377 - 7391

~%

353280-43-0 structure

353280-43-0

Literature: Blanc-Delmas, Elodie; Lebegue, Nicolas; Wallez, Valerie; Leclerc, Veronique; Yous, Said; Carato, Pascal; Farce, Amaury; Bennejean, Caroline; Renard, Pierre; Caignard, Daniel-Henri; Audinot-Bouchez, Valerie; Chomarat, Pascale; Boutin, Jean; Hennuyer, Nathalie; Louche, Katie; Carmona, Maria Carmen; Staels, Bart; Penicaud, Luc; Casteilla, Louis; Lonchampt, Michel; Dacquet, Catherine; Chavatte, Philippe; Berthelot, Pascal; Lesieur, Daniel Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 22 p. 7377 - 7391

~%

353280-43-0 structure

353280-43-0

Literature: Blanc-Delmas, Elodie; Lebegue, Nicolas; Wallez, Valerie; Leclerc, Veronique; Yous, Said; Carato, Pascal; Farce, Amaury; Bennejean, Caroline; Renard, Pierre; Caignard, Daniel-Henri; Audinot-Bouchez, Valerie; Chomarat, Pascale; Boutin, Jean; Hennuyer, Nathalie; Louche, Katie; Carmona, Maria Carmen; Staels, Bart; Penicaud, Luc; Casteilla, Louis; Lonchampt, Michel; Dacquet, Catherine; Chavatte, Philippe; Berthelot, Pascal; Lesieur, Daniel Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 22 p. 7377 - 7391

~%

353280-43-0 structure

353280-43-0

Literature: Blanc-Delmas, Elodie; Lebegue, Nicolas; Wallez, Valerie; Leclerc, Veronique; Yous, Said; Carato, Pascal; Farce, Amaury; Bennejean, Caroline; Renard, Pierre; Caignard, Daniel-Henri; Audinot-Bouchez, Valerie; Chomarat, Pascale; Boutin, Jean; Hennuyer, Nathalie; Louche, Katie; Carmona, Maria Carmen; Staels, Bart; Penicaud, Luc; Casteilla, Louis; Lonchampt, Michel; Dacquet, Catherine; Chavatte, Philippe; Berthelot, Pascal; Lesieur, Daniel Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 22 p. 7377 - 7391
Precursor  3

DownStream  0