CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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FL9450500
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CHEMICAL NAME :
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Chelidonine, hydrochloride
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CAS REGISTRY NUMBER :
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4312-31-6
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LAST UPDATED :
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199109
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DATA ITEMS CITED :
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2
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MOLECULAR FORMULA :
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C20-H19-N-O5.Cl-H
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MOLECULAR WEIGHT :
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389.86
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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>2 gm/kg
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TOXIC EFFECTS :
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Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Behavioral - tremor
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REFERENCE :
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PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 41,125,1989
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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1300 mg/kg
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TOXIC EFFECTS :
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Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Behavioral - tremor
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REFERENCE :
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PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 41,125,1989
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