CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
RO0548600
-
CHEMICAL NAME :
-
1,3,4-Oxadiazol-2-amine, 5-phenyl-, monohydrochloride
-
CAS REGISTRY NUMBER :
-
1905-75-5
-
LAST UPDATED :
-
199203
-
DATA ITEMS CITED :
-
3
-
MOLECULAR FORMULA :
-
C8-H7-N3-O.Cl-H
-
MOLECULAR WEIGHT :
-
197.64
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
LDLo - Lowest published lethal dose
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
440 mg/kg
-
TOXIC EFFECTS :
-
Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)
-
REFERENCE :
-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,726,1961
-
TYPE OF TEST :
-
LD - Lethal dose
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Primate - monkey
-
DOSE/DURATION :
-
>400 mg/kg
-
TOXIC EFFECTS :
-
Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)
-
REFERENCE :
-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,726,1961
-
TYPE OF TEST :
-
LD - Lethal dose
-
ROUTE OF EXPOSURE :
-
Intravenous
-
SPECIES OBSERVED :
-
Primate - monkey
-
DOSE/DURATION :
-
>60 mg/kg
-
TOXIC EFFECTS :
-
Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)
-
REFERENCE :
-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,726,1961
|