75969-83-4

75969-83-4 structure

Name: 11-Hydroxycanthin-6-one
Chemical Name: 11-hydroxy-canthin-6-one
CAS Number: 75969-83-4
Molecular Formula: C₁₄H₈N₂O₂
Molecular Weight: 236.22600
Catalog: Research Areas Cancer
Create Date: 2016-05-14 10:21:02
Modify Date: 2024-01-31 20:26:32
11-Hydroxycanthin-6-one, a canthin-6-one alkaloid, is an antitumor agent which shows potent cytotoxic activity[1][2].

Name	11-hydroxy-canthin-6-one
Synonyms	CANTHIN-6-ONE,11-HYDROXY Amalorin HMS2268C24 11-Hydroxycanthin-6-one 11-Hydroxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one

Description	11-Hydroxycanthin-6-one, a canthin-6-one alkaloid, is an antitumor agent which shows potent cytotoxic activity[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Fukamiya N, et, al. Antitumor agents: LXXXVII. Cytotoxic antileukemic canthin-6-one alkaloids from Brucea antidysenterica and the structure activity relationships of their related derivatives. Planta Med. 1987 Apr;53(2):140-3. [2]. Miyake K, et, al. Canthin-6-one alkaloids and a tirucallanoid from Eurycoma longifolia and their cytotoxic activity against a human HT-1080 fibrosarcoma cell line. Nat Prod Commun. 2010 Jan;5(1):17-22.