Top Suppliers:I want be here
Related CAS#:
1158522-08-7 940364-43-2
134104-43-1 131615-57-1
6906-52-1 930439-75-1
1018584-77-4 1375289-11-4
849349-65-1 644991-43-5

3471-05-4

3471-05-4 structure
3471-05-4 structure
  • Name: Anabase
  • Chemical Name: 3-(2,3,4,5-tetrahydropyridin-6-yl)pyridine
  • CAS Number: 3471-05-4
  • Molecular Formula: C10H12N2
  • Molecular Weight: 160.22
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel nAChR
  • Create Date: 2016-05-25 22:00:03
  • Modify Date: 2024-01-10 18:53:12
  • Anabaseine, an alkaloid, stimulates a wide variety of animal nicotinic acetylcholine receptors (AChRs), especially the neuromuscular receptors and α7 AChRs[1].
Name 3-(2,3,4,5-tetrahydropyridin-6-yl)pyridine
Synonyms anabaseine dihydrochloride
2,3'-BIPYRIDINE,3,4,5,6-TETRAHYDRO
Anabaseine
3,4,5,6-tetrahydro-2,3'-bipyridine
Description Anabaseine, an alkaloid, stimulates a wide variety of animal nicotinic acetylcholine receptors (AChRs), especially the neuromuscular receptors and α7 AChRs[1].
Related Catalog
In Vitro anabaseine (3.6 μmol/kg; subcutaneous injection) has a peak effect values of 50%, 85%, 62% for acetylcholine, dopamine and norepinephrine, respectively [1][2] . anabaseine act as neuromuscular agonists on the frog rectus abdominis muscle whit a EC50 of 0.25-0.74 μM[1].
References

[1]. [1] Kem W, et al. The Nemertine Toxin Anabaseine and Its Derivative DMXBA (GTS-21): Chemical and Pharmacological Properties. Mar Drugs. 2006;4(3):255-273.

[2]. [2] Summers KL et al. Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex. Jpn J Pharmacol. 1997 Jun;74(2):139-46.
Density 1.09g/cm3
Boiling Point 263.9ºC at 760mmHg
Molecular Formula C10H12N2
Molecular Weight 160.22
Flash Point 113.4ºC
Exact Mass 160.10000
PSA 25.25000
LogP 1.49020
Index of Refraction 1.596

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DW1890000
CHEMICAL NAME :
2,3'-Bipyridine, 3,4,5,6-tetrahydro-
CAS REGISTRY NUMBER :
3471-05-4
BEILSTEIN REFERENCE NO. :
0125981
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H12-N2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4200 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 32,684,1976
HS Code 2933399090
HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Chemsrc provides CAS#:3471-05-4 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 3471-05-4 | Chemsrc address: https://www.chemsrc.com/en/baike/524000.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved