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34816-55-2

34816-55-2 structure
34816-55-2 structure
  • Name: Moxestrol
  • Chemical Name: (8S,9S,11S,13S,14S,17R)-17-ethynyl-11-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
  • CAS Number: 34816-55-2
  • Molecular Formula: C21H26O3
  • Molecular Weight: 326.42900
  • Create Date: 2018-07-06 11:30:11
  • Modify Date: 2024-01-14 11:51:16

Name (8S,9S,11S,13S,14S,17R)-17-ethynyl-11-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
Synonyms 11beta-Methoxyethinylestradiol
Moxestrolum
Moxestrol
RU 2858
Density 1.221g/cm3
Boiling Point 477.715ºC at 760 mmHg
Molecular Formula C21H26O3
Molecular Weight 326.42900
Flash Point 242.714ºC
Exact Mass 326.18800
PSA 49.69000
LogP 3.23750
Index of Refraction 1.609

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RC8945000
CHEMICAL NAME :
19-Nor-17-alpha-pregna-1,3,5(10)-trien-20-yne-3,17-di ol, 11-beta-methoxy-
CAS REGISTRY NUMBER :
34816-55-2
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C21-H26-O3
MOLECULAR WEIGHT :
326.47
WISWESSER LINE NOTATION :
L E5 B666TTT&J CO1 E1 FQ F1UU1 OQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
SPECIES OBSERVED :
Rodent - hamster
DOSE/DURATION :
400 mg/kg/39W-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
50 ug/kg
SEX/DURATION :
female 16-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Effects on Newborn - delayed effects
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
250 ug/kg
SEX/DURATION :
female 16-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - urogenital system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
1250 ug/kg
SEX/DURATION :
female 16-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - live birth index (measured after birth)

MUTATION DATA

TEST SYSTEM :
Rodent - hamster
DOSE/DURATION :
160 mg/kg/20W (Continuous)
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 311,191,1994

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34816-55-2 structure

34816-55-2

Literature: Azadian Boulanger; Bertin 1973 , vol. 8, # 4 p. 451 - 454

~%

34816-55-2 structure

34816-55-2

Literature: Azadian Boulanger; Bertin 1973 , vol. 8, # 4 p. 451 - 454

~%

34816-55-2 structure

34816-55-2

Literature: Azadian Boulanger; Bertin 1973 , vol. 8, # 4 p. 451 - 454

~%

34816-55-2 structure

34816-55-2

Literature: Azadian Boulanger; Bertin 1973 , vol. 8, # 4 p. 451 - 454

~%

34816-55-2 structure

34816-55-2

Literature: Azadian Boulanger; Bertin 1973 , vol. 8, # 4 p. 451 - 454