Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-(benzoylamino)-N-(4-chlorophenyl)-3-methyl-4-isothiazolecarboxamide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

51287-57-1

51287-57-1 structure

51287-57-1 structure

Name: 5-(benzoylamino)-N-(4-chlorophenyl)-3-methyl-4-isothiazolecarboxamide
Chemical Name: 5-benzamido-N-(4-chlorophenyl)-3-methyl-1,2-thiazole-4-carboxamide
CAS Number: 51287-57-1
Molecular Formula: C₁₈H₁₄ClN₃O₂S
Molecular Weight: 371.84100
Create Date: 2016-09-28 08:19:42
Modify Date: 2022-05-29 18:14:18

Name	5-benzamido-N-(4-chlorophenyl)-3-methyl-1,2-thiazole-4-carboxamide
Synonyms	Wratizolin T-15 Denotivir 3-Methyl-5-benzoylaminoisothiazole-4-carboxylic acid p-chlorophenylamide p-Chlorophenylamide of 3-methyl-5-benzoylaminoizothiazole-4-carboxylic acid ITCL

Density	1.44g/cm3
Boiling Point	360ºC at 760mmHg
Molecular Formula	C₁₈H₁₄ClN₃O₂S
Molecular Weight	371.84100
Flash Point	171.5ºC
Exact Mass	371.05000
PSA	99.33000
LogP	4.75550
Index of Refraction	1.716

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NX8155650

CHEMICAL NAME :: 4-Isothiazolecarboxamide, 5-(benzoylamino)-N-(p-chlorophenyl)-3-methyl-

CAS REGISTRY NUMBER :: 51287-57-1

LAST UPDATED :: 199406

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C18-H14-Cl-N3-O2-S

MOLECULAR WEIGHT :: 371.86

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 28,393,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 330 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation

REFERENCE :: AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 28,393,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 28,393,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 219 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation

REFERENCE :: AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 28,393,1980