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14448-67-0

14448-67-0 structure
14448-67-0 structure

Name 3-methyl-2-benzothiazolinone hydrazone hydrochloride
Synonyms 3-Methyl-2(3H)-benzothiazolonehydrazonehydrochloride
2-Benzothiazolinone,3-methyl-,hydrazone,hydrochloride
3-Methylbenzothiazol-2(3H)-onehydrazoneHCl
3-Methyl-2-benzothiazolinone hydrazone HCI
3-METHYL-2-BENZOTHIAZOLINONE HYDRAZONE HCL
3-METHYLBENZOTHIAZOL-2-ONE HYDRAZONE HYDROCHLORIDE
MBTH HCL
3-Methyl-2-BenzothiazolinoneHydrazoneHcl(Mbth)
2(3H)-Benzothiazolone,3-methyl-,hydrazone,hydrochloride
2-Hydrazono-3-methyl-2,3-dihydrobenzo[d]thiazole hydrochloride
Boiling Point 369.6ºC at 760 mmHg
Melting Point 276-278℃(分解)
Molecular Formula C8H10ClN3S
Molecular Weight 215.70300
Flash Point 177.4ºC
Exact Mass 215.02800
PSA 71.55000
LogP 2.51650
Vapour Pressure 8.02E-06mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DL7160200
CHEMICAL NAME :
2(3H)-Benzothiazolone, 3-methyl-, hydrazone, hydrochloride
CAS REGISTRY NUMBER :
14448-67-0
LAST UPDATED :
199806
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C8-H9-N3-S.Cl-H
MOLECULAR WEIGHT :
215.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
149 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes Gastrointestinal - other changes
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>16 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
177 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
12300 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
1 mg/plate
REFERENCE :
TIHEEC Toxicology and Industrial Health. (Princeton Scientific Pub. Co., POB 2155, Princeton, NJ 08540) V.1- 1985- Volume(issue)/page/year: 4,23,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6634 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1358 (estimated) No. of Female Employees: 956 (estimated)