Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Amisometradine
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Huang

DC Chemicals Limited
China
Product Name: Amisometradine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2,4(1H,3H)-Pyrimidinedione,6-amino-3-methyl-1-(2-methyl-2-propen-1-yl)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

550-28-7

550-28-7 structure

Name: Amisometradine
Chemical Name: 6-amino-3-methyl-1-(2-methylprop-2-enyl)pyrimidine-2,4-dione
CAS Number: 550-28-7
Molecular Formula: C₉H₁₃N₃O₂
Molecular Weight: 195.21800
Create Date: 2018-04-11 08:00:00
Modify Date: 2024-01-05 21:30:28
Amisometradine is a diuretic which may be used in the treatment of congestive heart failure.

Name	6-amino-3-methyl-1-(2-methylprop-2-enyl)pyrimidine-2,4-dione
Synonyms	Aminoisometradin 6-Amino-1-metallyl-3-methylpyrimidine-2,4-dione AMISOMETRADINE Aminoisometradine Amisometradin Rolicton 6-Amino-1-methallyl-3-methyl-1H-pyrimidin-2,4-dion Amisometradinum [INN-Latin] 6-Amino-3-methyl-1-(2-methylallyl)uracil Uracil,6-amino-3-methyl-1-(2-methylallyl) 6-amino-1-methallyl-3-methyl-1H-pyrimidine-2,4-dione 6-amino-3-methyl-1-(2-methyl-allyl)-1H-pyrimidine-2,4-dione Amisometradina [INN-Spanish]

Density	1.176g/cm3
Boiling Point	292.1ºC at 760 mmHg
Molecular Formula	C₉H₁₃N₃O₂
Molecular Weight	195.21800
Flash Point	130.5ºC
Exact Mass	195.10100
PSA	70.02000
LogP	0.28650
Index of Refraction	1.537

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YQ8800000

CHEMICAL NAME :: Uracil, 6-amino-3-methyl-1-(2-methylallyl)-

CAS REGISTRY NUMBER :: 550-28-7

BEILSTEIN REFERENCE NO. :: 0182347

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C9-H13-N3-O2

MOLECULAR WEIGHT :: 195.25

WISWESSER LINE NOTATION :: T6NVNVJ A1Y1&U1 C1 FZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1560 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 126,400,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 515 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 126,400,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 610 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,79,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 415 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,79,1989

HS Code	2933599090

89487-41-2

550-28-7

Literature: Papesch; Schroeder Journal of Organic Chemistry, 1951 , vol. 16, p. 1879,1881,1887

874517-48-3

550-28-7

Literature: Papesch; Schroeder Journal of Organic Chemistry, 1951 , vol. 16, p. 1879,1881,1887

366445-27-4

77-78-1

550-28-7

Literature: Papesch; Schroeder Journal of Organic Chemistry, 1951 , vol. 16, p. 1879,1881,1887

Precursor 2
874517-48-3 77-78-1
DownStream 0

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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