Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3,3-(p-Chlorobenzylideno)-bis-4-hydroksykumaryn [Polish]
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4322-59-2

4322-59-2 structure

4322-59-2 structure

Name: 3,3-(p-Chlorobenzylideno)-bis-4-hydroksykumaryn [Polish]
Chemical Name: 3-[(4-chlorophenyl)-(4-hydroxy-2-oxochromen-3-yl)methyl]-4-hydroxychromen-2-one
CAS Number: 4322-59-2
Molecular Formula: C₂₅H₁₅ClO₆
Molecular Weight: 446.83600
Create Date: 2016-04-08 07:23:16
Modify Date: 2024-01-02 17:15:04

Name	3-[(4-chlorophenyl)-(4-hydroxy-2-oxochromen-3-yl)methyl]-4-hydroxychromen-2-one
Synonyms	3,3'-((4-chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) PCBD COUMARIN,3,3'-(p-CHLOROBENZYLIDENE)BIS(4-HYDROXY 3,3'-(4-chlorobenzylidene)-bis[4-hydroxycoumarin] 3,3'-(p-Chlorobenzylideno)-bis-4-hydroksykumaryn [Polish] 3,3'-(4-chlorophenylmethylene)-bis-4-hydroxycoumarin 3,3'-(p-Chlorobenzylidene)bis(4-hydroxycoumarin)

Density	1.575g/cm3
Boiling Point	625.7ºC at 760 mmHg
Molecular Formula	C₂₅H₁₅ClO₆
Molecular Weight	446.83600
Flash Point	332.2ºC
Exact Mass	446.05600
PSA	100.88000
LogP	5.14420
Index of Refraction	1.742

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GN4978000

CHEMICAL NAME :: Coumarin, 3,3'-(p-chlorobenzylidene)bis(4-hydroxy-

CAS REGISTRY NUMBER :: 4322-59-2

LAST UPDATED :: 199512

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C25-H15-Cl-O6

MOLECULAR WEIGHT :: 446.85

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 820 mg/kg

TOXIC EFFECTS :: Cardiac - other changes Vascular - BP lowering not characterized in autonomic section

REFERENCE :: DIPHAH Dissertationes Pharmaceuticae. (Warsaw, Poland) V.1-17, 1949-65. For publisher information, see PJPPAA. Volume(issue)/page/year: 17,163,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 158 mg/kg

TOXIC EFFECTS :: Cardiac - other changes Vascular - BP lowering not characterized in autonomic section

REFERENCE :: DIPHAH Dissertationes Pharmaceuticae. (Warsaw, Poland) V.1-17, 1949-65. For publisher information, see PJPPAA. Volume(issue)/page/year: 17,163,1965

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Cardiac - other changes Vascular - BP lowering not characterized in autonomic section

REFERENCE :: DIPHAH Dissertationes Pharmaceuticae. (Warsaw, Poland) V.1-17, 1949-65. For publisher information, see PJPPAA. Volume(issue)/page/year: 17,163,1965 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 221 mg/kg/7D-I

TOXIC EFFECTS :: Related to Chronic Data - death

REFERENCE :: DIPHAH Dissertationes Pharmaceuticae. (Warsaw, Poland) V.1-17, 1949-65. For publisher information, see PJPPAA. Volume(issue)/page/year: 17,163,1965

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 110 mg/kg/11D-I

TOXIC EFFECTS :: Related to Chronic Data - death

REFERENCE :: DIPHAH Dissertationes Pharmaceuticae. (Warsaw, Poland) V.1-17, 1949-65. For publisher information, see PJPPAA. Volume(issue)/page/year: 17,163,1965

HS Code	2932209090

1076-38-6 structure

1076-38-6

104-88-1 structure

104-88-1

~10%

4322-59-2 structure

4322-59-2

Literature: Heravi, Majid M.; Nahavandi, Fatemeh; Sadjadi, Samaheh; Oskooie, Hossein A.; Bamoharram, Fatemeh F. Synthetic Communications, 2010 , vol. 40, # 4 p. 498 - 503

1076-38-6 structure

1076-38-6

2362-79-0 structure

2362-79-0

~%

4322-59-2 structure

4322-59-2

Literature: Manolov, Ilia I. Tetrahedron Letters, 1998 , vol. 39, # 19 p. 3041 - 3042

Precursor 3
1076-38-6 104-88-1 2362-79-0
DownStream 0

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%