3772-55-2

3772-55-2 structure

Name: Abieta-8,11,13-trien-18-ol
Chemical Name: dehydroabietadienol
CAS Number: 3772-55-2
Molecular Formula: C₂₀H₃₀O
Molecular Weight: 286.452
Catalog: Natural product Moss
Create Date: 2016-09-06 14:06:28
Modify Date: 2024-01-01 23:07:15
Dehydroabietinol is an abietane diterpenoid. Dehydroabietinol has kinase inhibition activity for spleen tyrosine kinase (SYK) with an IC50 value of 46.4 μM. Dehydroabietinol can be used for the research of immune-mediated disease[1].

Name	dehydroabietadienol
Synonyms	1-Phenanthrenemethanol, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)- [(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanol Dehydroabietinol Abieta-8,11,13-trien-18-ol

Description	Dehydroabietinol is an abietane diterpenoid. Dehydroabietinol has kinase inhibition activity for spleen tyrosine kinase (SYK) with an IC50 value of 46.4 μM. Dehydroabietinol can be used for the research of immune-mediated disease[1].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Syk Research Areas >> Inflammation/Immunology
In Vitro	Dehydroabietinol 对脾酪氨酸激酶 SYK 具有激酶抑制活性，IC50 值为 46.4 μM[1]。
References	[1]. Jun-Bo Gao, et al. Isolation, Characterization, and Structure-Activity Relationship Analysis of Abietane Diterpenoids from Callicarpa bodinieri as Spleen Tyrosine Kinase Inhibitors. J Nat Prod. 2018 Apr 27;81(4):998-1006.

Hazard Codes	Xi