478082-99-4

478082-99-4 structure

Name: Ro4368554
Chemical Name: 3-(benzenesulfonyl)-7-(4-methylpiperazin-1-yl)-1H-indole
CAS Number: 478082-99-4
Molecular Formula: C₁₉H₂₁N₃O₂S
Molecular Weight: 355.45400
Create Date: 2017-04-28 00:08:20
Modify Date: 2024-04-09 12:02:37
Ro4368554 is a 5-HT6 receptor antagonist. RO4368554 acts selectively at 5-HT6 receptors where it binds with a greater than 100-fold selectivity over other monoamine receptor subtypes (-log M pKi = 9.4 at 5-HT6 and 7.1 at 5-HT2A).

Name	3-(benzenesulfonyl)-7-(4-methylpiperazin-1-yl)-1H-indole
Synonyms	7-(4-methyl-1-piperazinyl)-3-(phenylsulfonyl)-1H-Indole 3-benzenesulfonyl-7-(4-methyl-piperazin-1-yl)-1H-indole 3-phenylsulfonyl-7-(4-methyl-piperazin-1-yl)-1H-indole 1H-Indole,7-(4-methyl-1-piperazinyl)-3-(phenylsulfonyl)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Hazard Codes	Xn
RIDADR	NONH for all modes of transport