CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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TK8065000
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CHEMICAL NAME :
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Piperazine, 1-(3-(p-aminophenoxy)propyl)-4-(o-methoxyphenyl)-, dihydrochloride
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CAS REGISTRY NUMBER :
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76487-32-6
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LAST UPDATED :
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198910
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C20-H27-N3-O2.2Cl-H
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MOLECULAR WEIGHT :
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414.42
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WISWESSER LINE NOTATION :
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T6N DNTJ A3OR DZ& DR BO1 &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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416 mg/kg
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TOXIC EFFECTS :
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Behavioral - changes in motor activity (specific assay) Behavioral - antipsychotic
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REFERENCE :
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DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 6,346,1981
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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319 mg/kg
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TOXIC EFFECTS :
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Behavioral - changes in motor activity (specific assay) Behavioral - antipsychotic
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REFERENCE :
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DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 6,346,1981
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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158 mg/kg
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TOXIC EFFECTS :
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Behavioral - changes in motor activity (specific assay) Behavioral - antipsychotic
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REFERENCE :
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DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 6,346,1981
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