144602-02-8

144602-02-8 structure

Name: Endothelin-1 (11-21) trifluoroacetate salt
Chemical Name: [Cys11-Cys15]-endothelin-1(11-21)
CAS Number: 144602-02-8
Molecular Formula: C₆₈H₉₂N₁₄O₁₅S₂
Molecular Weight: 1409.67000
Catalog: Signaling Pathways GPCR/G Protein Endothelin Receptor
Create Date: 2018-12-22 16:01:16
Modify Date: 2024-01-11 08:47:35
IRL 1038 is an endothelin B receptor selective antagonist with a Ki of 6-11 nM[1].

Name	[Cys11-Cys15]-endothelin-1(11-21)
Synonyms	cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp

Description	IRL 1038 is an endothelin B receptor selective antagonist with a Ki of 6-11 nM[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Endothelin Receptor Research Areas >> Neurological Disease
Target	Ki: 6-11 nM (endothelin B receptors), 0.4-0.7 μM (endothelin A receptors)[1]
References	[1]. Urade Y, et al. An endothelin B receptor-selective antagonist: IRL 1038, [Cys11-Cys15]-endothelin-1(11-21). FEBS Lett. 1992 Oct 12;311(1):12-6. doi: 10.1016/0014-5793(92)81355-p.