15302-10-0

15302-10-0 structure
15302-10-0 structure
  • Name: Clibucaine
  • Chemical Name: N-(2,4-dichlorophenyl)-3-piperidin-1-ylbutanamide
  • CAS Number: 15302-10-0
  • Molecular Formula: C15H20Cl2N2O
  • Molecular Weight: 315.24
  • Catalog: Research Areas Others
  • Create Date: 2018-03-06 08:00:00
  • Modify Date: 2024-01-23 19:11:49
  • Clibucaine is a piperidine derivative possessing local anesthetic properties. Clibucaine can be used as a local anesthetic agent[1].

Name N-(2,4-dichlorophenyl)-3-piperidin-1-ylbutanamide
Synonyms Clibucaina
3-Piperidino-buttersaeure-(2,4-dichlor-anilid)
Clibucaine
Clibucaina [INN-Spanish]
3-piperidino-butyric acid-(2,4-dichloro-anilide)
Clibucainum [INN-Latin]
Description Clibucaine is a piperidine derivative possessing local anesthetic properties. Clibucaine can be used as a local anesthetic agent[1].
Related Catalog
References

[1]. Dennie Van Den Heuvel, et al. Gastro-retentive oral dosage unit containing a local anaesthetic. Patent, WO2023094100A1.

Density 1.255g/cm3
Boiling Point 466.8ºC at 760mmHg
Molecular Formula C15H20Cl2N2O
Molecular Weight 315.24
Flash Point 236.1ºC
Exact Mass 314.09500
PSA 35.83000
LogP 4.78380
Vapour Pressure 6.86E-09mmHg at 25°C
Index of Refraction 1.585

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TN3712310
CHEMICAL NAME :
1-Piperidinepropionanilide, 2',4'-dichloro-beta-methyl-
CAS REGISTRY NUMBER :
15302-10-0
BEILSTEIN REFERENCE NO. :
0249881
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C15-H20-Cl2-N2-O
MOLECULAR WEIGHT :
315.27
WISWESSER LINE NOTATION :
T6NTJ AY1&1VMR BG DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HCACAV Helvetica Chimica Acta. (Verlag Helvetica Chimica Acta, Postfach, CH-4002 Basel, Switzerland) V.1- 1918- Volume(issue)/page/year: 38,1085,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
220 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HCACAV Helvetica Chimica Acta. (Verlag Helvetica Chimica Acta, Postfach, CH-4002 Basel, Switzerland) V.1- 1918- Volume(issue)/page/year: 38,1085,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
59 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HCACAV Helvetica Chimica Acta. (Verlag Helvetica Chimica Acta, Postfach, CH-4002 Basel, Switzerland) V.1- 1918- Volume(issue)/page/year: 38,1085,1955
HS Code 2933399090

~%

15302-10-0 structure

15302-10-0

Literature: Wilder Smith; Hofstetter Helvetica Chimica Acta, 1955 , vol. 38, p. 1085,1089,1091

~%

15302-10-0 structure

15302-10-0

Literature: Wilder Smith; Hofstetter Helvetica Chimica Acta, 1955 , vol. 38, p. 1085,1089,1091

~%

15302-10-0 structure

15302-10-0

Literature: Wilder Smith; Hofstetter Helvetica Chimica Acta, 1955 , vol. 38, p. 1085,1089,1091
Precursor  2

DownStream  0

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%