CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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JI4727000
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CHEMICAL NAME :
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1,3-Dioxolo(4,5-g)isoquinoline, 5-(1,1-dimethylpentyl)-7-methyl-, hydrochloride
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CAS REGISTRY NUMBER :
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17105-26-9
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LAST UPDATED :
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198502
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DATA ITEMS CITED :
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2
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MOLECULAR FORMULA :
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C18-H23-N-O2.Cl-H
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MOLECULAR WEIGHT :
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321.88
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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283 mg/kg
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TOXIC EFFECTS :
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Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)
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REFERENCE :
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YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 88,1197,1968
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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69 mg/kg
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TOXIC EFFECTS :
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Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)
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REFERENCE :
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YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 88,1197,1968
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