- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: SCH 50911 hydrochloride
- Price:
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Huang
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: (2R-TRANS)-2-(3,4-DIHYDROXYPHENYL)-3,4-DIHYDRO-3-METHOXY-2H-1-BENZOPYRAN-5,7-DIOL
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
160415-07-6
160415-07-6 structure
- Name: SCH 50911 hydrochloride
- Chemical Name: (2s)-(+)-5,5-dimethyl-2-morpholineacetic acid
- CAS Number: 160415-07-6
- Molecular Formula: C8H16ClNO3
- Molecular Weight: 173.21000
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel GABA Receptor
- Create Date: 2018-12-26 13:09:47
- Modify Date: 2024-09-14 06:56:05
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SCH 50911 hydrochloride, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1 μM. SCH 50911 hydrochloride antagonizes GABA(B) autoreceptors, increasing the electrically-stimulated 3H overflow with an IC50 of 3 μM.
| Name | (2s)-(+)-5,5-dimethyl-2-morpholineacetic acid |
|---|---|
| Synonyms | (+)-(2S)-5,5-Dimethyl-2-morpholineacetic acid hydrochloride |
| Description | SCH 50911 hydrochloride, (+)-(S)-5,5-dimethylmorpholinyl-2-acetic acid, a selective, orally-active and competitive γ-Aminobutyric acid B GABA(B) receptor antagonist, binds to GABA(B) receptor with IC50 of 1.1 μM. SCH 50911 hydrochloride antagonizes GABA(B) autoreceptors, increasing the electrically-stimulated 3H overflow with an IC50 of 3 μM. |
|---|---|
| Related Catalog | |
| Target |
GABA(B):1.1 μM (IC50) |
| References |
| Density | 1.055 g/cm3 |
|---|---|
| Boiling Point | 305.5ºC at 760 mmHg |
| Molecular Formula | C8H16ClNO3 |
| Molecular Weight | 173.21000 |
| Flash Point | 138.6ºC |
| Exact Mass | 173.10500 |
| PSA | 58.56000 |
| LogP | 0.55690 |
| Vapour Pressure | 0.000187mmHg at 25°C |
| Index of Refraction | 1.444 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H317 |
| Precautionary Statements | P280 |
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| HS Code | 2934999090 |
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |