16416-35-6

16416-35-6 structure

Name: Pristane-d40
Chemical Name: 2,6,10,14-tetramethylpentadecane-d40
CAS Number: 16416-35-6
Molecular Formula: C₁₉D₄₀
Molecular Weight: 308.76700
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-06-22 18:20:08
Modify Date: 2024-01-02 18:36:07
Pristane-d40 is the deuterium labeled Pristane[1]. Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil[2]. Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat[3].

Name	2,6,10,14-tetramethylpentadecane-d40
Synonyms	Pristan-1-ol 1-Pentadecanol,2,6,10,14-tetramethyl norphytanol Pristan-d40 2H,6H,10H,14H-octacosadeuterio-2,6,10,14-tetrakis-trideuteriomethyl-pentadecane 2,6,10,14-tetramethyl-pentadecan-1-ol

Description	Pristane-d40 is the deuterium labeled Pristane[1]. Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil[2]. Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat[3].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. J J Turner, et al. Krypton Fluoride: Preparation by the Matrix Isolation Technique. Science. 1963 May 31;140(3570):974-5. [3]. Jens Holmberg,et al. Pristane, a non-antigenic adjuvant, induces MHC class II-restricted, arthritogenic T cells in the rat. J Immunol. 2006 Jan 15176(2):1172-9.