17590-01-1

17590-01-1 structure

17590-01-1 structure

Name: Amfetaminil
Chemical Name: 2-phenyl-2-(1-phenylpropan-2-ylamino)acetonitrile
CAS Number: 17590-01-1
Molecular Formula: C₁₇H₁₈N₂
Molecular Weight: 250.33800
Create Date: 2018-05-14 08:00:00
Modify Date: 2024-01-11 06:43:17

Name	2-phenyl-2-(1-phenylpropan-2-ylamino)acetonitrile
Synonyms	dl-Amphetaminil Aponeuron Amfetaminilum [INN-Latin] Amphetaminil Amfetaminilo [INN-Spanish] amfetaminil AN 1 AN 1 (pharmaceutical) AN 1 (VAN) (1-methyl-2-phenyl-ethylamino)-phenyl-acetonitrile

Density	1.061g/cm3
Boiling Point	405.2ºC at 760mmHg
Melting Point	81-85ºC
Molecular Formula	C₁₇H₁₈N₂
Molecular Weight	250.33800
Flash Point	198.8ºC
Exact Mass	250.14700
PSA	35.82000
LogP	3.86298
Vapour Pressure	8.95E-07mmHg at 25°C
Index of Refraction	1.572

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AM1050000

CHEMICAL NAME :: Acetonitrile, ((alpha-methylphenethyl)amino)phenyl-

CAS REGISTRY NUMBER :: 17590-01-1

LAST UPDATED :: 199706

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C17-H18-N2

MOLECULAR WEIGHT :: 250.37

WISWESSER LINE NOTATION :: NCYR&MY1&1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 37600 ug/kg

TOXIC EFFECTS :: Cardiac - pulse rate increase, without fall in BP Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 24,823,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 58800 ug/kg

TOXIC EFFECTS :: Cardiac - pulse rate increase, without fall in BP Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 24,823,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 95100 ug/kg

TOXIC EFFECTS :: Cardiac - pulse rate increase, without fall in BP Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 24,823,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 182 mg/kg

TOXIC EFFECTS :: Cardiac - pulse rate increase, without fall in BP Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 24,823,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 491 mg/kg

TOXIC EFFECTS :: Cardiac - pulse rate increase, without fall in BP Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 24,823,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 58 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,335,1972

HS Code	2926909090

151-50-8 structure

151-50-8

2706-50-5 structure

2706-50-5

100-52-7 structure

100-52-7

~%

17590-01-1 structure

17590-01-1

Literature: Journal of medicinal chemistry, , vol. 14, # 10 p. 1013 - 1015

151-50-8 structure

151-50-8

100-52-7 structure

100-52-7

60-15-1 structure

60-15-1

~%

17590-01-1 structure

17590-01-1

Literature: Zhurnal Organicheskoi Khimii, , vol. 3, # 8 p. 1513 - 1518,1470 - 1474

Precursor 4
151-50-8 2706-50-5 100-52-7 60-15-1
DownStream 0

HS Code	2926909090
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%