169209-66-9

169209-66-9 structure

Name: MTPG
Chemical Name: (±)-α-Methyl-(4-tetrazolylphenyl)glycine
CAS Number: 169209-66-9
Molecular Formula: C₁₀H₁₁N₅O₂
Molecular Weight: 233.23
Catalog: Signaling Pathways GPCR/G Protein mGluR
Create Date: 2018-12-25 19:32:41
Modify Date: 2024-04-07 22:02:55
MTPG is a potent mGluR2 and mGluR3 antagonist. MTPG can block the induction of brain ischemic tolerance induced by cerebral ischemic preconditioning. MTPG also significantly attenuates the inhibitory effect of L-CCG-1 on the KCl-evoked dopamine release[1].

Name	(±)-α-Methyl-(4-tetrazolylphenyl)glycine
Synonyms	MFCD00672653 2-amino-2-[4-(tetrazol-1-yl)phenyl]propanoic acid

Description	MTPG is a potent mGluR2 and mGluR3 antagonist. MTPG can block the induction of brain ischemic tolerance induced by cerebral ischemic preconditioning. MTPG also significantly attenuates the inhibitory effect of L-CCG-1 on the KCl-evoked dopamine release[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	mGluR2, mGluR 3[1]
References	[1]. Chaki S, et al. Group II metabotropic glutamate receptor-mediated regulation of dopamine release from slices of rat nucleus accumbens. Neurosci Lett. 2006;404(1-2):182-186. [2]. Feng RF, Li WB, Liu HQ, et al. Sheng Li Xue Bao. 2003;55(3):303-310.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
HS Code	2933990090

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%