118457-16-2

118457-16-2 structure
118457-16-2 structure

Name (1S)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-[[(2S)-2-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl]amino]ethanol
Synonyms UNII-GMK2E335DQ
Levonebivolol
l-nebivolol
Density 1.309g/cm3
Boiling Point 600.5ºC at 760mmHg
Molecular Formula C22H25F2NO4
Molecular Weight 405.43500
Flash Point 316.9ºC
Exact Mass 405.17500
PSA 70.95000
LogP 2.75450
Vapour Pressure 2.88E-15mmHg at 25°C
Index of Refraction 1.58

~60%

118457-16-2 structure

118457-16-2

Literature: EGIS GYOGYSZERGYAR RT. Patent: WO2004/41805 A1, 2004 ; Location in patent: Page 68-69 ;

~65%

118457-16-2 structure

118457-16-2

Literature: ZACH SYSTEM S.P.A.; MARAGNI, Paolo; MICHIELETTO, Ivan; VOLPICELLI, Raffaella; SORIATO, Giorgio; FOLETTO, Johnny; COTARCA, Livius; VERZINI, Massimo Patent: WO2010/49455 A1, 2010 ; Location in patent: Page/Page column 10-11 ;

~%

118457-16-2 structure

118457-16-2

Literature: WO2008/64826 A1, ; Page/Page column 26-27 ;
Precursor  3

DownStream  0