681482-24-6

681482-24-6 structure

Name: 1-benzyl-4-[4-(trifluoromethyl)phenyl]-3,6-dihydro-2H-pyridine
Chemical Name: 1-benzyl-4-[4-(trifluoromethyl)phenyl]-3,6-dihydro-2H-pyridine
CAS Number: 681482-24-6
Molecular Formula: C₁₉H₁₈F₃N
Molecular Weight: 317.34800
Create Date: 2016-05-21 08:29:23
Modify Date: 2024-01-20 00:38:01

Name	1-benzyl-4-[4-(trifluoromethyl)phenyl]-3,6-dihydro-2H-pyridine

Molecular Formula	C₁₉H₁₈F₃N
Molecular Weight	317.34800
Exact Mass	317.13900
PSA	3.24000
LogP	4.93260

58778-51-1

~98%

681482-24-6

Literature: PFIZER PRODUCTS INC. Patent: WO2008/12623 A1, 2008 ; Location in patent: Page/Page column 67-68 ; WO 2008/012623 A1

936231-01-5

402-43-7

~82%

681482-24-6

Literature: JANSSEN PHARMACEUTICA N.V. Patent: WO2008/79255 A1, 2008 ; Location in patent: Page/Page column 28-29 ;

936231-01-5

455-13-0

~10%

681482-24-6

Literature: JANSSEN PHARMACEUTICA N.V. Patent: WO2008/79255 A1, 2008 ; Location in patent: Page/Page column 19-22 ;

3612-20-2

~28%

681482-24-6

Literature: KALYSPSYS, INC.; NOBLE, Stewart A.; OSHIRO, Guy; MALECHA, James W.; ZHAO, Cunxiang; ROBINSON, Carmen K. M.; DURON, Sergio G.; SERTIC, Michael; LINDSTROM, Andrew; SHIAU, Andrew; BAYNE, Christopher; KAHRAMAN, Mehmet; LOU, Boliang; GOVEK, Steven Patent: WO2006/55187 A1, 2006 ; Location in patent: Page/Page column 42-43 ; WO 2006/055187 A1

3612-20-2

402-43-7

681482-24-6

Literature: Zhang, Lei; Brodney, Michael A.; Candler, John; Doran, Angela C.; Duplantier, Allen J.; Efremov, Ivan V.; Evrard, Edel; Kraus, Kenneth; Ganong, Alan H.; Haas, Jessica A.; Hanks, Ashley N.; Jenza, Keith; Lazzaro, John T.; Maklad, Noha; McCarthy, Sheryl A.; Qian, Weimin; Rogers, Bruce N.; Rottas, Melinda D.; Schmidt, Christopher J.; Siuciak, Judith A.; Tingley III, F. David; Zhang, Andy Q. Journal of Medicinal Chemistry, 2011 , vol. 54, # 6 p. 1724 - 1739

402-43-7

681482-24-6

Literature: Nencetti, Susanna; Mazzoni, Maria R.; Ortore, Gabriella; Lapucci, Annalina; Giuntini, Janette; Orlandini, Elisabetta; Banti, Irene; Nuti, Elisa; Lucacchini, Antonio; Giannaccini, Gino; Rossello, Armando European Journal of Medicinal Chemistry, 2011 , vol. 46, # 3 p. 825 - 834

Precursor 4
58778-51-1 402-43-7 455-13-0 3612-20-2
DownStream 0

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930439-75-1	1018584-77-4