494-79-1

494-79-1 structure

Name: melarsoprol
Chemical Name: [2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol
CAS Number: 494-79-1
Molecular Formula: C₁₂H₁₅AsN₆OS₂
Molecular Weight: 398.33900
Catalog: Research Areas Infection
Create Date: 2018-02-10 08:00:00
Modify Date: 2024-01-02 08:57:15
Melarsoprol (Arsobal), a melaminophenylarsine-type trivalent organic arsenical, is an important drug for African trypanosomiasis. Melarsoprol is also active against leukemia cell lines and plasma cells from myeloma patients. Melarsoprol increases the biliary output of GSH in rats[1].

Name	[2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol
Synonyms	Mel B melarsenoxide-BAL Melarsoprol Melarsoprolum [INN-Latin] Melarsoprolum 2-(p-(4,6-Diamino-s-triazin-2-ylamino)phenyl)-1,3,2-dithiarsolane-4-methanol {2-[4-(4,6-diamino-[1,3,5]triazin-2-ylamino)-phenyl]-[1,3,2]dithiarsolan-4-yl}-methanol EINECS 207-793-4 Melarsenoxid-BAL 1,3,2-Dithiarsolane-4-methanol,2-(4-((4,6-diamino-1,3,5-triazin-2-yl)amino)phenyl) Arsobal

Description	Melarsoprol (Arsobal), a melaminophenylarsine-type trivalent organic arsenical, is an important drug for African trypanosomiasis. Melarsoprol is also active against leukemia cell lines and plasma cells from myeloma patients. Melarsoprol increases the biliary output of GSH in rats[1].
Related Catalog	Research Areas >> Infection
References	[1]. Z Gregus, et al. Role of glutathione in the biliary excretion of the arsenical drugs trimelarsan and melarsoprol. Biochem Pharmacol. 2000 Jun 1;59(11):1375-85.

5806-89-3

494-79-1

Precursor 1
5806-89-3
DownStream 0