Flazin
Modify Date: 2024-01-05 21:44:20
Flazin structure
|
Common Name | Flazin | ||
|---|---|---|---|---|
| CAS Number | 100041-05-2 | Molecular Weight | 308.28800 | |
| Density | 1.513g/cm3 | Boiling Point | 657.1ºC at 760mmHg | |
| Molecular Formula | C17H12N2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 351.2ºC | |
Use of FlazinFlazin is a non-enzymatic protein glycation inhibitor, also inhibits peroxynitrite (ONOO-), with an IC50 value of 85.31 μM for bovine serum albumin (BSA) glycation and an EC50 value of 71.99 μM for ONOO-. Flazin can be used for researching diabetes and neuronal disorders. Flazin also can used as a lipid droplet (LD) regulator against lipid disorders, and a xanthine oxidase (XOD) inhibitor[1][2][3]. |
| Name | 1-[5-(hydroxymethyl)furan-2-yl]-9H-pyrido[3,4-b]indole-3-carboxylic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Flazin is a non-enzymatic protein glycation inhibitor, also inhibits peroxynitrite (ONOO-), with an IC50 value of 85.31 μM for bovine serum albumin (BSA) glycation and an EC50 value of 71.99 μM for ONOO-. Flazin can be used for researching diabetes and neuronal disorders. Flazin also can used as a lipid droplet (LD) regulator against lipid disorders, and a xanthine oxidase (XOD) inhibitor[1][2][3]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 85.31 μM (BSA), 0.51 mM (XOD)[1][2] EC50: 71.99 μM (ONOO-)[1] |
| In Vitro | Flazin significantly decreases cellular triglyceride (TG) by 12.0-22.4% compared with modeling groups and improved the TG and free fatty acid profile[2]. Flazin efficiently reduces both cellular neutral lipid content by 17.4-53.9% and lipid droplets size by 10.0-35.3%[2]. Flazin exhibits xanthine oxidase inhibitory with an IC50 of 0.51 mM[3]. |
| References |
| Density | 1.513g/cm3 |
|---|---|
| Boiling Point | 657.1ºC at 760mmHg |
| Molecular Formula | C17H12N2O4 |
| Molecular Weight | 308.28800 |
| Flash Point | 351.2ºC |
| Exact Mass | 308.08000 |
| PSA | 99.35000 |
| LogP | 3.16660 |
| Vapour Pressure | 3.69E-18mmHg at 25°C |
| Index of Refraction | 1.771 |
| Flazine |
| 3-carboxylperlolyrine |
| Flazin |
| 9H-Pyrido[3,4-b]indole-3-carboxylic acid,1-[5-(hydroxymethyl)-2-furanyl] |