Ipatasertib-NH2 dihydrochloride structure
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Common Name | Ipatasertib-NH2 dihydrochloride | ||
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CAS Number | 1001264-73-8 | Molecular Weight | 488.84 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C21H28Cl3N5O2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Ipatasertib-NH2 dihydrochlorideIpatasertib-NH2 dihydrochloride is a ligand for target protein AKT for PROTAC (INY-03-041). INY-03-041 is composed of Ipatasertib-NH2, a ten-hydrocarbon linker, and a CRBN ligand Lenalidomide for E3 ubiquitin ligase[1]. |
Name | Ipatasertib-NH2 dihydrochloride |
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Description | Ipatasertib-NH2 dihydrochloride is a ligand for target protein AKT for PROTAC (INY-03-041). INY-03-041 is composed of Ipatasertib-NH2, a ten-hydrocarbon linker, and a CRBN ligand Lenalidomide for E3 ubiquitin ligase[1]. |
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Related Catalog | |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Molecular Formula | C21H28Cl3N5O2 |
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Molecular Weight | 488.84 |
Storage condition | 2-8°C |