Lercanidipine
Lercanidipine structure
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Common Name | Lercanidipine | ||
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| CAS Number | 100427-26-7 | Molecular Weight | 611.727 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 712.5±60.0 °C at 760 mmHg | |
| Molecular Formula | C36H41N3O6 | Melting Point | 118-120ºC | |
| MSDS | N/A | Flash Point | 384.7±32.9 °C | |
Use of LercanidipineLercanidipine is a calcium channel blocker of the dihydropyridine class.Target: Calcium ChannelLercanidipine is a calcium channel blocker of the dihydropyridine class, which works by relaxing and opening the blood vessels allowing the blood to circulate more freely around the body. Lercanidipine was effective and well-tolerated in patients with mild-to-moderate hypertension in the daily practice. The effectiveness and safety of the drug were independent of the degree of cardiovascular risk [1, 2]. |
| Name | 5-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
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| Synonym | More Synonyms |
| Description | Lercanidipine is a calcium channel blocker of the dihydropyridine class.Target: Calcium ChannelLercanidipine is a calcium channel blocker of the dihydropyridine class, which works by relaxing and opening the blood vessels allowing the blood to circulate more freely around the body. Lercanidipine was effective and well-tolerated in patients with mild-to-moderate hypertension in the daily practice. The effectiveness and safety of the drug were independent of the degree of cardiovascular risk [1, 2]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 712.5±60.0 °C at 760 mmHg |
| Melting Point | 118-120ºC |
| Molecular Formula | C36H41N3O6 |
| Molecular Weight | 611.727 |
| Flash Point | 384.7±32.9 °C |
| Exact Mass | 611.299561 |
| PSA | 113.69000 |
| LogP | 8.04 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.580 |
| HS Code | 2942000000 |
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~76%
Lercanidipine CAS#:100427-26-7 |
| Literature: Recordati Ireland Limited Patent: US2006/199849 A1, 2006 ; Location in patent: Page/Page column 7-8 ; |
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Lercanidipine CAS#:100427-26-7 |
| Literature: European Journal of Medicinal Chemistry, , vol. 33, # 5 p. 399 - 420 |
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Lercanidipine CAS#:100427-26-7 |
| Literature: European Journal of Medicinal Chemistry, , vol. 33, # 5 p. 399 - 420 |
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Lercanidipine CAS#:100427-26-7 |
| Literature: European Journal of Medicinal Chemistry, , vol. 33, # 5 p. 399 - 420 |
|
~%
Lercanidipine CAS#:100427-26-7 |
| Literature: European Journal of Medicinal Chemistry, , vol. 33, # 5 p. 399 - 420 |
|
~%
Lercanidipine CAS#:100427-26-7 |
| Literature: European Journal of Medicinal Chemistry, , vol. 33, # 5 p. 399 - 420 |
|
~%
Lercanidipine CAS#:100427-26-7 |
| Literature: US2006/199849 A1, ; Page/Page column 8 ; |
|
~%
Lercanidipine CAS#:100427-26-7 |
| Literature: European Journal of Medicinal Chemistry, , vol. 33, # 5 p. 399 - 420 |
| Precursor 9 | |
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| DownStream 1 | |
| HS Code | 2942000000 |
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| 1-[(3,3-diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
| 3-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 5-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
| 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester |
| lercarnidipine |
| 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester |
| methyl 1,1,N-trimethyl-N-(3,3-diphenylpropyl)-2-aminoethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5-dicarboxylate |
| masnidipine |
| Methyl 1,1-Dimethyl-2-[N-(3,3-diphenylpropyl)-N-methylamino]ethyl 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
| 1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methyl-2-propanyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate |
| Lercanidipine [INN] |
| UNII:V7XTJ4R0BH |
| Lercanil (TN) |
| (±)-2-((3,3-diphenylpropyl)(methyl)amino)-1,1-dimethylethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
| REC 15-2375 |
| MFCD00867978 |
| UNII-V7XTJ4R0BH |
| 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester |
| Lercanidipine |