(R)-Ambrisentan

Modify Date: 2024-02-03 13:28:00

(R)-Ambrisentan Structure
(R)-Ambrisentan structure
Common Name (R)-Ambrisentan
CAS Number 1007358-76-0 Molecular Weight 378.421
Density 1.2±0.1 g/cm3 Boiling Point 551.1±60.0 °C at 760 mmHg
Molecular Formula C22H22N2O4 Melting Point N/A
MSDS N/A Flash Point 287.1±32.9 °C

 Names

Name (2R)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 551.1±60.0 °C at 760 mmHg
Molecular Formula C22H22N2O4
Molecular Weight 378.421
Flash Point 287.1±32.9 °C
Exact Mass 378.157959
PSA 81.54000
LogP 6.24
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.593

 Synthetic Route

~77%

(R)-Ambrisentan Structure

(R)-Ambrisentan

CAS#:1007358-76-0

Literature: Sata, Kaushik Babubhai; Pandey, Bipin Patent: US2012/184573 A1, 2012 ; Location in patent: Page/Page column 10; 11 ;

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(R)-Ambrisentan Structure

(R)-Ambrisentan

CAS#:1007358-76-0

Literature: Sata, Kaushik Babubhai; Pandey, Bipin Patent: US2012/184573 A1, 2012 ;

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

Ambrisentan,(R)
UNII-Q1BX7HE63A
Benzenepropanoic acid, α-[(4,6-dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-phenyl-, (αR)-
(R)-ambrisentan
(2R)-2-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-3-methoxy-3,3-diphenylpropanoic acid
(|AS)-|A-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-|A-methoxy-|A-phenylbenzenepropanoic Acid
Ambrisentan
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