1-(4-pyridyl)piperazine

Modify Date: 2024-01-02 09:11:58

1-(4-pyridyl)piperazine structure	Common Name	1-(4-pyridyl)piperazine
	CAS Number	1008-91-9	Molecular Weight	163.220
	Density	1.1±0.1 g/cm3	Boiling Point	314.4±22.0 °C at 760 mmHg
	Molecular Formula	C₉H₁₃N₃	Melting Point	137-141 °C
	MSDS	Chinese USA	Flash Point	143.9±22.3 °C
	Symbol	GHS05	Signal Word	Danger

Name	1-(4-Pyridyl)piperazine
Synonym	More Synonyms

Density	1.1±0.1 g/cm3
Boiling Point	314.4±22.0 °C at 760 mmHg
Melting Point	137-141 °C
Molecular Formula	C₉H₁₃N₃
Molecular Weight	163.220
Flash Point	143.9±22.3 °C
Exact Mass	163.110947
PSA	28.16000
LogP	0.12
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.547

Material Safety Data Sheet

Section1. Identiﬁcation of the substance
Product Name: 1-(4-Pyridyl)piperazine
Synonyms:

Section2. Hazards identiﬁcation
Harmful by inhalation, in contact with skin, and if swallowed.

H314:Causes severe skin burns and eye damage
P280:Wear protective gloves/protective clothing/eye protection/face protection
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing
P310:Immediately call a POISON CENTER or doctor/physician

Section3. Composition/information on ingredients.
Ingredient name:1-(4-Pyridyl)piperazine
CAS number:1008-91-9

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
ﬂushing of the eyes by separating the eyelids with ﬁngers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire ﬁghting measures
In the event of a ﬁre involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualiﬁed
in the handling and use of potentially hazardous chemicals, who should take into account the ﬁre,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels, refrigerated.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not speciﬁed
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C9H13N3
Molecular weight: 163.2

Section10. Stability and reactivity
Conditions to avoid: Heat, ﬂames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
UN Number:UN3259 Class: 8 Packing group: II
Proper shipping name: AMINES, SOLID, CORROSIVE, N.O.S. OR POLYAMINES, SOLID, CORROSIVE, N.O.S. (1-
(4-Pyridyl)piperazine)

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.

SECTION 16 - ADDITIONAL INFORMATION
N/A

Symbol	GHS05
Signal Word	Danger
Hazard Statements	H314
Precautionary Statements	P280-P305 + P351 + P338-P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	C:Corrosive;
Risk Phrases	R34
Safety Phrases	S26-S36/37/39-S45
RIDADR	UN 3259 8/PG 2
WGK Germany	3
Packaging Group	II
Hazard Class	8
HS Code	2933990090

Precursor 10
CAS#:63980-43-8 1-Benzyl-4-(4-p... CAS#:110-85-0 Piperazine CAS#:626-61-9 4-chloropyridine CAS#:1120-87-2 4-Bromopyridine
CAS#:1143575-83-0 (R)-2-(2-chloro... CAS#:1143575-87-4 [1-(2-chloro-5-... CAS#:1143575-85-2 (2-chloro-5-oxo... CAS#:57260-71-6 N-Boc-piperazine
CAS#:74901-69-2 2,4-Dichloro-6,... CAS#:1143575-82-9 (R)-2-(2-chloro...
DownStream 2
CAS#:204693-44-7 3,5-Dibromo-N-{... CAS#:796856-41-2 1-(2,6-dichloro...

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%