4-(1,3-Oxazol-5-yl)aniline

Modify Date: 2024-01-11 21:11:31

4-(1,3-Oxazol-5-yl)aniline Structure
4-(1,3-Oxazol-5-yl)aniline structure
Common Name 4-(1,3-Oxazol-5-yl)aniline
CAS Number 1008-95-3 Molecular Weight 160.17300
Density 1.204g/cm3 Boiling Point 318.7ºC at 760mmHg
Molecular Formula C9H8N2O Melting Point 150ºC
MSDS N/A Flash Point 146.5ºC

 Names

Name 4-(5-Oxazolyl)aniline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.204g/cm3
Boiling Point 318.7ºC at 760mmHg
Melting Point 150ºC
Molecular Formula C9H8N2O
Molecular Weight 160.17300
Flash Point 146.5ºC
Exact Mass 160.06400
PSA 52.05000
LogP 2.50500
Vapour Pressure 0.000356mmHg at 25°C
Index of Refraction 1.599

 MSDS

Name: 4-(1 3-Oxazol-5-yl)aniline tech Material Safety Data Sheet
Synonym:
CAS: 1008-95-3
Section 1 - Chemical Product MSDS Name:4-(1 3-Oxazol-5-yl)aniline tech Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
1008-95-3 4-(1,3-Oxazol-5-yl)aniline unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 1008-95-3: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 148 - 150 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C9H8N2O
Molecular Weight: 160.18

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 1008-95-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
4-(1,3-Oxazol-5-yl)aniline - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 1008-95-3: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 1008-95-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 1008-95-3 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases 26-36/37/39
HS Code 2934999090

 Synthetic Route

~91%

4-(1,3-Oxazol-5-yl)aniline Structure

4-(1,3-Oxazol-5...

CAS#:1008-95-3

Literature: F2G LTD Patent: WO2006/123145 A1, 2006 ; Location in patent: Page/Page column 66-67 ;

~80%

4-(1,3-Oxazol-5-yl)aniline Structure

4-(1,3-Oxazol-5...

CAS#:1008-95-3

Literature: Cell Therapeutics, Inc. Patent: US2004/204386 A1, 2004 ;

~63%

4-(1,3-Oxazol-5-yl)aniline Structure

4-(1,3-Oxazol-5...

CAS#:1008-95-3

Literature: Primas, Nicolas; Bouillon, Alexandre; Lancelot, Jean-Charles; Rault, Sylvain Tetrahedron, 2009 , vol. 65, # 32 p. 6348 - 6353

~%

4-(1,3-Oxazol-5-yl)aniline Structure

4-(1,3-Oxazol-5...

CAS#:1008-95-3

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 12 p. 2059 - 2063

~%

4-(1,3-Oxazol-5-yl)aniline Structure

4-(1,3-Oxazol-5...

CAS#:1008-95-3

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 12 p. 2059 - 2063

~%

4-(1,3-Oxazol-5-yl)aniline Structure

4-(1,3-Oxazol-5...

CAS#:1008-95-3

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 12 p. 2059 - 2063

~%

4-(1,3-Oxazol-5-yl)aniline Structure

4-(1,3-Oxazol-5...

CAS#:1008-95-3

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 12 p. 2059 - 2063

~%

4-(1,3-Oxazol-5-yl)aniline Structure

4-(1,3-Oxazol-5...

CAS#:1008-95-3

Literature: US6344465 B1, ; Page column 17-18 ;

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

4-(1,3-OXAZOL-5-YL)ANILINE
4-(1,3-Oxazol-5-yl)aniline
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