2-Methoxybenzenesulfonyl chloride

Modify Date: 2024-01-02 12:33:01

2-Methoxybenzenesulfonyl chloride Structure
2-Methoxybenzenesulfonyl chloride structure
Common Name 2-Methoxybenzenesulfonyl chloride
CAS Number 10130-87-7 Molecular Weight 206.647
Density 1.4±0.1 g/cm3 Boiling Point 305.1±25.0 °C at 760 mmHg
Molecular Formula C7H7ClO3S Melting Point 50-54ºC
MSDS N/A Flash Point 138.3±23.2 °C

 Names

Name 2-Methoxybenzenesulfonyl chloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 305.1±25.0 °C at 760 mmHg
Melting Point 50-54ºC
Molecular Formula C7H7ClO3S
Molecular Weight 206.647
Flash Point 138.3±23.2 °C
Exact Mass 205.980438
PSA 51.75000
LogP 1.90
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.536
Storage condition 2-8°C

 MSDS

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 2-Methoxybenzenesulfonyl chloride
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H317:May cause an allergic skin reaction
P280:Wear protective gloves/protective clothing/eye protection/face protection

Section3. Composition/information on ingredients.
Ingredient name:2-Methoxybenzenesulfonyl chloride
CAS number:10130-87-7

Section4. First aid measures
Immediately wash skin with copious amounts of water for at least 15 minutes while removing
Skin contact:
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Not specified
Appearance:
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula:C7H7ClO3S
Molecular weight:206.6

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, hydrogen chloride, sulfur oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
UN Number:UN3261 Class: 8 Packing group: III
Proper shipping name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (2-Methoxybenzenesulfonyl chloride)

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xi
Risk Phrases R34
Safety Phrases 26-36/37/39
RIDADR UN 3261
Packaging Group
HS Code 2909309090

 Synthetic Route

~82%

2-Methoxybenzenesulfonyl chloride Structure

2-Methoxybenzen...

CAS#:10130-87-7

Literature: Milburn, Robert R.; Snieckus, Victor Angewandte Chemie - International Edition, 2004 , vol. 43, # 7 p. 892 - 894

~82%

2-Methoxybenzenesulfonyl chloride Structure

2-Methoxybenzen...

CAS#:10130-87-7

Literature: Debergh, J. Robb; Niljianskul, Nootaree; Buchwald, Stephen L. Journal of the American Chemical Society, 2013 , vol. 135, # 29 p. 10638 - 10641

~22%

2-Methoxybenzenesulfonyl chloride Structure

2-Methoxybenzen...

CAS#:10130-87-7

Literature: Binisti, Carine; Assogba, Leon; Touboul, Estera; Mounier, Carine; Huet, Jack; Ombetta, Jean-Edouard; Dong, Chang Zhi; Redeuilh, Catherine; Heymans, Francoise; Godfroid, Jean-Jacques European Journal of Medicinal Chemistry, 2001 , vol. 36, # 10 p. 809 - 828

~%

2-Methoxybenzenesulfonyl chloride Structure

2-Methoxybenzen...

CAS#:10130-87-7

Literature: Journal of Organic Chemistry, , vol. 68, # 21 p. 8274 - 8276

~%

2-Methoxybenzenesulfonyl chloride Structure

2-Methoxybenzen...

CAS#:10130-87-7

Literature: Australian Journal of Chemistry, , vol. 6, p. 318

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2-Methoxybenzenesulfonyl chloride Structure

2-Methoxybenzen...

CAS#:10130-87-7

Literature: Chemische Berichte, , vol. 90, p. 841,843

~%

2-Methoxybenzenesulfonyl chloride Structure

2-Methoxybenzen...

CAS#:10130-87-7

Literature: Journal of the Chemical Society [Section] C: Organic, , p. 1265 - 1267

 Customs

HS Code 2909309090
Summary 2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Synonyms

Benzenesulfonyl chloride, 2-methoxy-
2-Methoxy-benzenesulfonyl chloride
2-Methoxybenzenesulfonyl chloride
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