(2R,4R)-4-(((9H-FLUOREN-9-YL)METHOXY)CARBONYLAMINO)-1-(TERT-BUTOXYCARBONYL)PYRROLIDINE-2-CARBOXYLICACID

Modify Date: 2024-04-03 14:54:10

(2R,4R)-4-(((9H-FLUOREN-9-YL)METHOXY)CARBONYLAMINO)-1-(TERT-BUTOXYCARBONYL)PYRROLIDINE-2-CARBOXYLICACID Structure
(2R,4R)-4-(((9H-FLUOREN-9-YL)METHOXY)CARBONYLAMINO)-1-(TERT-BUTOXYCARBONYL)PYRROLIDINE-2-CARBOXYLICACID structure
Common Name (2R,4R)-4-(((9H-FLUOREN-9-YL)METHOXY)CARBONYLAMINO)-1-(TERT-BUTOXYCARBONYL)PYRROLIDINE-2-CARBOXYLICACID
CAS Number 1018332-24-5 Molecular Weight 452.500
Density 1.3±0.1 g/cm3 Boiling Point 650.2±55.0 °C at 760 mmHg
Molecular Formula C25H28N2O6 Melting Point N/A
MSDS N/A Flash Point 347.0±31.5 °C

 Names

Name (4R)-4-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-1-{[(2-methyl-2- propanyl)oxy]carbonyl}-D-proline
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 650.2±55.0 °C at 760 mmHg
Molecular Formula C25H28N2O6
Molecular Weight 452.500
Flash Point 347.0±31.5 °C
Exact Mass 452.194733
PSA 108.66000
LogP 3.86
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.627

 Synthetic Route

~%

(2R,4R)-4-(((9H-FLUOREN-9-YL)METHOXY)CARBONYLAMINO)-1-(TERT-BUTOXYCARBONYL)PYRROLIDINE-2-CARBOXYLICACID Structure

(2R,4R)-4-(((9H...

CAS#:1018332-24-5

Literature: Zanardi, Franca; Burreddu, Paola; Rassu, Gloria; Auzzas, Luciana; Battistini, Lucia; Curti, Claudio; Sartori, Andrea; Nicastro, Giuseppe; Menchi, Gloria; Cini, Nicoletta; Bottonocetti, Anna; Raspanti, Silvia; Casiraghi, Giovanni Journal of Medicinal Chemistry, 2008 , vol. 51, # 6 p. 1771 - 1782

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

(2R-cis)-2-(Fluoromethyl)-4-hydroxy-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester
(2R,4R)-N-Boc-2-(fluoromethyl)-4-hydroxypyrrolidine
(2R,4R)-1-(tert-butoxycarbonyl)-4-N-(9-fluorenylmethoxycarbonyl)aminoproline
(2R,4R)-1-(tert-butoxycarbonyl)-4-hydroxypiperidine-2-carboxylic acid
(4R)-4-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-proline
(2R,4R)-1-(tert-butoxycarbonyl)-4-hydroxy-2-(fluoromethyl)pyrrolidine
1-Pyrrolidinecarboxylicacid,2-(fluoromethyl)-4-hydroxy-,1,1-dimethylethyl ester,(2R-cis)-(9CI)
1,2-Pyrrolidinedicarboxylic acid, 4-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, 1-(1,1-dimethylethyl) ester, (2R,4R)-
(2R,4R)-tert-Butyl 2-(fluoromethyl)-4-hydroxypyrrolidine-1-carboxylate