aristolochic acid sodium salt

Modify Date: 2024-01-15 16:00:11

aristolochic acid sodium salt Structure
aristolochic acid sodium salt structure
Common Name aristolochic acid sodium salt
CAS Number 10190-99-5 Molecular Weight 363.25400
Density N/A Boiling Point 615.5ºC at 760 mmHg
Molecular Formula C17H10NNaO7 Melting Point N/A
MSDS Chinese USA Flash Point 326ºC
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

 Use of aristolochic acid sodium salt


Aristolochic acid sodium salt (Sodium aristolate 1) is a component of some Chinese herbal medicines and is responsible for nephrotoxicity. It is a prodrug that is activated by reduction of nitro groups to amines, resulting in the formation of cytotoxic DNA adducts.

 Names

Name Aristolochic acid I sodium salt
Synonym More Synonyms

 aristolochic acid sodium salt Biological Activity

Description Aristolochic acid sodium salt (Sodium aristolate 1) is a component of some Chinese herbal medicines and is responsible for nephrotoxicity. It is a prodrug that is activated by reduction of nitro groups to amines, resulting in the formation of cytotoxic DNA adducts.
Related Catalog

 Chemical & Physical Properties

Boiling Point 615.5ºC at 760 mmHg
Molecular Formula C17H10NNaO7
Molecular Weight 363.25400
Flash Point 326ºC
Exact Mass 363.03500
PSA 113.64000
LogP 2.52520
Vapour Pressure 5.24E-16mmHg at 25°C
Water Solubility H2O: 50 mg/mL

 Safety Information

Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger
Hazard Statements H301 + H311 + H331-H351
Precautionary Statements Missing Phrase - N15.00950417-P261-P280-P302 + P352 + P312-P304 + P340 + P312-P403 + P233
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes T
Risk Phrases R23/24/25
Safety Phrases S22;S45;S36/S37/S39
RIDADR UN 2811
WGK Germany 3
RTECS SF8281000
Packaging Group III
Hazard Class 6.1(b)

 Articles2

More Articles
Loss of tumour suppressor PTEN expression in renal injury initiates SMAD3- and p53-dependent fibrotic responses.

J. Pathol. 236 , 421-32, (2015)

Deregulation of the tumour suppressor PTEN occurs in lung and skin fibrosis and diabetic and ischaemic renal injury. However, the potential role of PTEN and associated mechanisms in the progression of...

Drosophila TRPA1 channel mediates chemical avoidance in gustatory receptor neurons.

Proc. Natl. Acad. Sci. U. S. A. 107 , 8440-5, (2010)

Mammalian sweet, bitter, and umami taste is mediated by a single transduction pathway that includes a phospholipase C (PLC)beta and one cation channel, TRPM5. However, in insects such as the fruit fly...

 Synonyms

EINECS 233-463-4
sodium,8-methoxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylate
Top Suppliers:I want be here


Get all suppliers and price by the below link:

aristolochic acid sodium salt suppliers

aristolochic acid sodium salt price